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. 2022 May 27;27(11):3476. doi: 10.3390/molecules27113476

Table 5.

Analgesic activity of test compounds.

Compound Dose, mg/kg Writhing Number Decrease in the Vinegar Writhing Number (%)
control - 106.2 ± 11.2 100
sodium diclofenac 8 49.5 ± 10.7 53.3
2a 25 95.4 ± 10.9 10.2
2b 25 55.6 ± 11.3 * 47.6
2d 25 62.2 ± 11.2 * 41.4
2e 25 53.7 ± 11.6 * 49.4
3a 25 96.8 ± 11.2 8.8
3b 25 83.8 ± 10.4 21.1
3c 25 57.2 ± 7.5 * 46.1
3d 25 75.4 ± 10.5 29.0
3e 25 50.2 ± 10.3 * 52.7
2f 25 54.4 ± 12.3 48.8

Note: *—p < 0.05 compared to control.