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. 2022 May 27;16(5):e0010433. doi: 10.1371/journal.pntd.0010433

Fig 6. Differentially expressed canonical signaling pathways in Vesiculovax-vaccinated macaques.

Fig 6

Heatmap of the most significantly upregulated and downregulated canonical pathways in survivor versus fatal subjects based on functional enrichment of differentially expressed transcripts (Benjamini-Hochberg false discovery rate (FDR) corrected p-value less than 0.05) in vaccinated survivor (n = 10) versus fatal (n = 8) samples. Cohorts were examined at early (3 DPI), mid (6 DPI), and late disease (10 DPI, or the terminal time point in fatal cases). DPI, days post infection. Corresponding z-scores were plotted. Red indicates high expression; blue indicates low expression; white indicates no difference in expression; gray indicates insufficient transcripts mapping to the pathway.