Table 1.
Sample | Concentration (μg/mL) | α-Glucosidase | α-Amylase | ||
---|---|---|---|---|---|
Percent Inhibition |
IC50 (μg/mL) | Percent Inhibition |
IC50 (μg/mL) | ||
Fi.Cr | 1000 | 64.44 ± 0.09 *** | 232.10 | 66.90 ± 0.72 *** | 218.19 |
500 | 56.87 ± 0.39 *** | 57.12 ± 0.89 *** | |||
250 | 51.83 ± 1.07 *** | 52.64 ± 1.38 *** | |||
125 | 44.23 ± 0.44 *** | 45.40 ± 0.93 *** | |||
62.5 | 36.29 ± 0.43 *** | 35.22 ± 0.94 *** | |||
Fi.Hex | 1000 | 61.50 ± 2.26 *** | 340.56 | 65.50 ± 2.26 *** | 249.85 |
500 | 54.01 ± 0.42 *** | 56.01 ± 0.42 *** | |||
250 | 45.07 ± 0.62 *** | 49.07 ± 0.62 *** | |||
125 | 39.70 ± 0.35 *** | 43.70 ± 0.35 *** | |||
62.5 | 34.73 ± 0.66 *** | 35.73 ± 0.66 *** | |||
Fi.EtAc | 1000 | 71.69 ± 0.77 *** | 117.54 | 73.60 ± 1.63 *** | 96.82 |
500 | 63.67 ± 0.61 *** | 66.82 ± 0.85 *** | |||
250 | 56.44 ± 0.51 *** | 61.25 ± 1.40 *** | |||
125 | 51.76 ± 0.58 *** | 53.10 ± 0.60 *** | |||
62.5 | 43.54 ± 0.50 *** | 44.61 ± 0.43 *** | |||
Fi.Chf | 1000 | 61.23 ± 0.22 *** | 296.86 | 63.48 ± 0.25 *** | 259.11 |
500 | 55.45 ± 0.90 *** | 56.47 ± 0.04 *** | |||
250 | 46.90 ± 0.60 *** | 48.47 ± 0.44 *** | |||
125 | 41.00 ± 0.30 *** | 42.44 ± 0.09 *** | |||
62.5 | 37.90 ± 0.45 *** | 37.43 ± 1.39 *** | |||
Fi.Aq | 1000 | 57.85 ± 0.56 *** | 429.39 | 57.79 ± 0.62 *** | 398.46 |
500 | 51.64 ± 0.75 *** | 52.45 ± 0.49 *** | |||
250 | 44.58 ± 0.77 *** | 46.75 ± 0.58 *** | |||
125 | 38.75 ± 0.63 *** | 38.73 ± 0.64 *** | |||
62.5 | 32.58 ± 0.70 *** | 33.47 ± 0.56 *** | |||
Acarbose | 1000 | 96.00 ± 0.30 | 17.28 | 82.43 ± 0.52 | 12.84 |
500 | 90.61 ± 0.43 | 74.03 ± 0.64 | |||
250 | 84.03 ± 0.86 | 71.56 ± 0.49 | |||
125 | 77.58 ± 0.77 | 67.05 ± 0.49 | |||
62.5 | 71.48 ± 0.74 | 63.26 ± 0.93 |
All values are taken as mean ± SEM (n = 3). Two-way ANOVA followed by Bonferoni test were followed. Values significantly different in comparison to standard drug, i.e., *** = p < 0.001.