Table 2.
Proteins with fold changes >2.0 or <0.5.
| Protein IDs | Protein Name | Gene Name | p-Value | Fold Change Aflibercept/NaCl |
|---|---|---|---|---|
| P17948 | Vascular endothelial growth factor receptor 1 * | FLT1 | p < 0.001 | 46.42 |
| P0DOX5; P01857 | Ig gamma-1 chain C region ** | IGHG1 | p < 0.001 | 18.9 |
| P35968 | Vascular endothelial growth factor receptor 2 *** | KDR | p < 0.001 | 5.07 |
| P13618 | ATP synthase-coupling factor 6, mitochondria | ATP5PF | 0.13 | 0.47 |
| Q95274; P62328 | Thymosin beta-4; Hematopoietic system regulatory peptide | TMSB4X | 0.16 | 0.43 |
| P02475 | Alpha-crystallin A chain | CRYAA | 0.07 | 0.27 |
* VEGFR-1 immunoglobulin domain of aflibercept. ** Ig gamma-1 chain C region of the aflibercept fusion protein. *** VEGFR-2 immunoglobulin domain of aflibercept. p-values are from the Student’s t-test used to identify significantly changed proteins.