Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 May 25;27(11):3412. doi: 10.3390/molecules27113412

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The schematic representation of the PI3K/Akt/mTOR signaling pathway in BC. VEGF: vascular endothelial growth factor; NF-κB: nuclear factor kappa-B; EGF(R): epidermal growth factor (receptor); mTOR: mammalian target of rapamycin; PDK1/2: 3-phosphoinositide-dependent kinase-1/2; PI3K: phosphatidylinositol 3-kinase; MMP: matrix metalloprotein; PIP-3: phosphatidylinositol (3,4,5)-trisphosphate; Bcl-2: B-cell lymphoma 2; mTORC-2: mTOR complex 2; VRGF: vascular endothelial growth factor; Bad: Bcl-2 antagonist of cell death. This figure is reproduced from Dong et al. [56] (Creative Commons Attribution License (CC BY 4.0)).