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. 2022 Jun 4;27(11):3617. doi: 10.3390/molecules27113617

Figure 3.

Figure 3

Evaluation of CM-398 for antinociceptive effects in the mouse formalin-induced inflammation assay. Dose-dependent antinociception of sigma-2 receptor ligand CM-398 followed i.p. administration. Control mice were treated with saline (0.9%, i.p.) or morphine (10 mg/kg, i.p.). All points represent summed time spent licking ± SEM administered to 5–10 mice for all points.