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Proportion of patients with humoral immune response to SARS-CoV-2 spike protein (anti-S) are shown in total and for various subgroups (Anti-SARS-CoV-2 spike protein antibodies cutoff >12 AU/ml). Baseline IgG values indicate the severity of the humoral immunodeficiency disease at start of immunoglobulin replacement therapy. P values are calculated by Chi-square test. Anti-SARS-CoV-2 spike protein antibodies (anti-S).
