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Prevalence of common symptoms from enrollment to 12 months of age. Symptoms were graded by the investigators as ‘absent’, ‘occasional’, ‘frequent’, or ‘all the time’. P-values are shown for the comparison of frequent and persistent symptoms at Visit 0 (V0) compared to Visit 1 (V1) after 1 month. V2, V3, and V4 were follow-up visits after 2, 3, and 4 months, respectively; the final study visit (V5) occurred at 12 months of age.
