Table 2.
Hazard Ratios (HRs) and 95% confidence intervals (CIs) for all-cause and cause-specific mortality according to the quintiles of dietary folate.
| Quartile of Nutrient Intake | Ptrend | ||||
|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | ||
| Men | |||||
| All-cause mortality | |||||
| Crude Model | Ref | 0.89 (0.84–0.95) |
0.77 (0.72–0.83) |
0.65 (0.60–0.71) |
<0.001 |
| Multivariable Model | Ref | 0.91 (0.86–0.97) |
0.86 (0.80–0.92) |
0.77 (0.71–0.85) |
<0.001 |
| Cardiovascular mortality | |||||
| Crude Model | Ref | 0.80 (0.71–0.91) |
0.64 (0.55–0.75) |
0.53 (0.44–0.63) |
<0.001 |
| Multivariable Model | Ref | 0.81 (0.71–0.92) |
0.71 (0.61–0.83) |
0.59 (0.48–0.72) |
<0.001 |
| Cancer mortality | |||||
| Crude Model | Ref | 0.82 (0.72–0.93) |
0.77 (0.66–0.89) |
0.57 (0.48–0.68) |
<0.001 |
| Multivariable Model | Ref | 0.87 (0.77–0.99) |
0.89 (0.77–1.04) |
0.68 (0.56–0.84) |
0.001 |
| Women | |||||
| All-cause mortality | |||||
| Crude Model | Ref | 1.01 (0.94–1.07) |
0.91 (0.84–0.98) |
0.85 (0.78–0.93) |
<0.001 |
| Multivariable Model | Ref | 0.91 (0.85–0.97) |
0.87 (0.81–0.95) |
0.86 (0.78–0.95) |
<0.001 |
| Cardiovascular mortality | |||||
| Crude Model | Ref | 0.91 (0.79–1.05) |
0.71 (0.59–0.86) |
0.58 (0.46–0.71) |
<0.001 |
| Multivariable Model | Ref | 0.82 (0.70–0.95) |
0.69 (0.57–0.83) |
0.53 (0.41–0.69) |
<0.001 |
| Cancer mortality | |||||
| Crude Model | Ref | 0.97 (0.84–1.13) |
1.04 (0.88–1.24) |
0.79 (0.65–0.97) |
0.115 |
| Multivariable Model | Ref | 0.93 (0.80–1.08) |
1.05 (0.88–1.25) |
0.82 (0.66–1.03) |
0.342 |
Crude HR did not adjust for anything. Multivariable HR adjusted for age, race/ethnicity, BMI, family income–poverty ratio, smoking status, drinking status, leisure-time physical activity, total energy intake, diabetes, hypertension, and cardiovascular disease.