Table 2.

Characterization of methotrexate patches.

Characteristics
F. Code	pH	Thickness (mm)	Weight Uniformity (mg)	% Moisture Content	% Swelling Index	% Drug Content	Water Transmission Rate g/m2/24 h	Folding Endurance(d)	Tensile Strength Kg/cm2
F1	5.5	0.57 ± 0.12	80.14 ± 0.13	10.67 ± 1.42	61.85 ± 1.46	94.58 ± 3.14	2.13 ± 0.15	66 ± 3.14	11.23 ± 0.23
F2	5.7	0.61 ± 0.07	85.61 ± 0.05	11.12 ± 1.73	63.58 ± 0.29	96.23 ± 2.08	3.88 ± 0.34	69 ± 1.21	11.54 ± 0.18
F3	5.6	0.64 ± 0.02	89.54 ± 0.12	11.53 ± 1.67	65.61 ± 1.26	97.81 ± 1.17	4.23 ± 0.67	71 ± 2.14	11.93 ± 0.56
F4	5.7	0.67 ± 0.03	91.23 ± 0.07	11.92 ± 1.64	69.82 ± 0.37	98.37 ± 0.56	4.61 ± 0.52	73 ± 2.31	12.13 ± 0.93
F5	5.8	0.71 ± 0.05	95.44 ± 0.10	12.45 ± 1.83	75.32 ± 1.21	98.54 ± 1.31	4.82 ± 0.61	74 ± 3.16	12.64 ± 0.28
F6	5.6	0.54 ± 0.03	77.75 ± 0.09	10.38 ± 1.10	56.16 ± 0.85	97.32 ± 1.33	2.61 ± 0.17	67 ± 2.32	9.55 ± 0.39
F7	5.3	0.52 ± 0.10	76.34 ± 0.06	10.13 ± 1.48	46.23 ± 0.33	96.58 ± 2.36	2.43 ± 0.32	65 ± 2.59	8.96 ± 0.46
F8	5.4	0.50 ± 0.05	72.43 ± 0.08	9.78 ± 1.73	41.63 ± 1.59	94.81 ± 1.46	2.28 ± 0.27	62 ± 1.43	8.59 ± 0.72
F9	5.2	0.47 ± 0.09	70.68 ± 0.05	9.01 ± 1.47	36.98 ± 0.19	92.57 ± 3.22	2.15 ± 0.63	61 ± 1.23	8.21 ± 0.33

Data are expressed as mean ± SD.