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. 2022 Jun 2;11(11):1499. doi: 10.3390/plants11111499

Figure 4.

Figure 4

Effect of shallot extract (SE, 0.1 mg/mL) on expressions of genes associated with androgenetic alopecia: (a) SRD5A1; (b) SRD5A2; (c) SRD5A3; (d) SHH; (e) SMO; (f) GIL1; (g) CTNNB1; (h) VEGF. DU-145 human prostate cancer cells (DU-145) were used to observe the expressions of genes in the androgen pathway (SRD5A genes), whereas human hair follicle dermal papilla cells (hHFDPC) were used to study the remaining pathways. Different letters (a, b, and c) indicate statistical significance (p < 0.05) in comparison to control, finasteride (0.1 mg/mL), dutasteride (0.1 mg/mL), purmorphamine (0.1 mg/mL), and minoxidil (0.1 mg/mL).