Table 2.
Polymeric | Diffusional Impact | Kinetic Impact | ||||
---|---|---|---|---|---|---|
Carriers Loaded with SVN | Radius of Carrier, [cm] |
∆(Gt/G∞)/∆t0.5 [s−0.5] a |
Drug Diffusivity (D’), [cm2/s] | R-Square, Origin® |
kG × 106 [s−1] |
R-Square, Origin® |
PHB-micro-beads | 0.0125 | 0.196 | 8.72 × 10−10 | 0.994 | 3.75 | 0.964 |
PVA cryogel | 0.563 | 0.148 | 2.69 × 10−6 | 0.985 | 5.63 | 0.998 |
PVA/PHB composite | 0.563 | 0.203 | 5.05 × 10−6 | 0.997 | 2.29 | 0.968 |
a Gt and G∞ are the cumulative weight content of the SVN free fraction released at a time t and t → ∞, respectively, in accordance with diffusion mechanism.