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. 2022 May 31;61(1):87. doi: 10.3892/ijo.2022.5377

Figure 4.

Figure 4

CDCA5 knockdown inhibits the proliferation and migration of ccRCC cells in vitro. (A) Knockdown efficiency of CDCA5 in SN12-PM6 and 786-O cells following transfection was confirmed using western blot analysis. (B) CDCA5 knockdown reduced cell proliferation as shown by crystal violet staining. The viability rate of cells=(the OD values of treated groups/the OD values of the NC group) ×100%. Scale bar, 50 µm. (C) CDCA5 knockdown significantly suppressed the migration of SN12-PM6 and 786-O cells. Scale bar, 50 µm. Data are presented as the mean ± standard deviation from three independent experiments. **P<0.01, ***P<0.001 and ****P<0.0001 vs. negative control. CDCA5, cell division cycle-associated 5; ccRCC, clear cell renal cell carcinoma; NC, negative control.