Table 3.
Results from forward stepwise multivariable logistic regression measuring association between clinical factors and the likelihood of clinically significant discrepancy between NIBP and IABP*. All predetermined factors were entered into the models and only factors with significant association were reported. The models for each outcome measure showed both good fit of the independent variables and good discriminatory capability (higher AUROC**).
| Variables | OR | 95% CI | P | VIF |
|---|---|---|---|---|
| Outcome: Clinically Significant Blood Pressure Discrepancy1 | ||||
| SOFA – each unit | 1.33 | 1.02–1.73 | 0.034 | 2.0 |
| Serum lactate – each mmol/L | 1.27 | 1.003–1.60 | 0.047 | 2.1 |
| Any kidney disease | 0.03 | 0.002–0.51 | 0.015 | 2.6 |
| Bowel obstruction | 34 | 1.2–100+ | 0.035 | 1.4 |
| Secondary outcome: MAP difference ≥ 10 mm Hg2 | ||||
| SOFA – each unit | 1.17 | 1.03–1.3 | 0.012 | 1.9 |
| Peripheral artery disease | 6.7 | 1.3–33.5 | 0.021 | 1.1 |
| Incarcerated organs | 16.4 | 1.4–100+ | 0.027 | 1.1 |
Homes-Lemeshow test chi-square 4.5, D(f) = 8; P = 0.81; AUROC: 0.92.
Homes-Lemeshow test chi-square 6.5, D(f) = 8, P = 0.59; AUROC: 0.72.
AUROC, area under the receiver operating characteristic curve; OR, odds ratio; CI, confidence interval; D(f), degree of freedom; mmol/L, millimoles per liter; IABP, invasive arterial blood pressure; NIBP, non-invasive blood pressure; SOFA, Sequential Organ Failure Assessment score; VIF, variance inflation factor.