Table 1.
Demographic features and laboratory findings of the participants.
| Control (n = 162) | FRI (n = 170) | P value | |
|---|---|---|---|
| Age (years) | 39 (28, 50) | 42 (28.50, 49) | 0.976 |
| Gender (male/female) | 95/67 | 145/25 | <0.001 |
| WBCs (×109/L) | 7.50 (6.10, 9.13) | 7.13 (5.96, 8.34) | 0.079 |
| Neutrophils (×109/L) | 4.83 (3.86, 6.93) | 4.16 (3.17, 5.39) | <0.001 |
| Lymphocytes (×109/L) | 1.73 (1.46, 2.07) | 2.05 (1.71, 2.50) | <0.001 |
| Monocytes (×109/L) | 0.47 (0.36, 0.64) | 0.51 (0.40, 0.63) | 0.174 |
| RBCs (×1012/L) | 4.41 (4.09, 4.82) | 4.72 (4.22, 5.05) | 0.002 |
| Hemoglobin (g/L) | 133 (121, 145) | 132.50 (114.75, 144.25) | 0.251 |
| Platelets (×109/L) | 227 (188.75, 267.25) | 278 (218.75, 353.25) | <0.001 |
| CRP (mg/L) | 2.90 (1.58, 8.82) | 4.49 (1.72, 10.04) | 0.244 |
| ESR (mm/h) | 25 (15, 41) | 20 (8, 34.25) | 0.005 |
| NLR | 2.73 (1.86, 4.35) | 1.97 (1.40, 2.55) | <0.001 |
| MLR | 0.26 (0.19, 0.39) | 0.24 (0.19, 0.32) | 0.009 |
| PLR | 132.70 (105.49, 174.56) | 133.31 (99.29, 174.05) | 0.694 |
| Positive rates of inflammation markers (events, %) | |||
| WBCs | 30, 18.52% | 14, 8.24% | 0.006 |
| CRP | 50, 30.86% | 53, 31.18% | 0.951 |
| ESR | 121, 74.69% | 97, 57.06% | 0.001 |
| Open fracture vs. closed fracture | 15/147 | 126/44 | <0.001 |
| Single site vs. multiple sites | 118/44 | 137/33 | 0.094 |
| Positive rate of culture (events, %) | 87, 51.18% | ||
| Monomicrobial infection vs. polymicrobial infection | 67/20 | ||
FRI: fracture-related infection; WBCs: white blood cells; RBCs: red blood cells; NLR: neutrophil-to-lymphocyte ratio; MLR: monocyte-to-lymphocyte ratio; PLR: platelet-to-lymphocyte ratio; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate.