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. 2022 Jun 10;17(5):1869–1888. doi: 10.1007/s11468-022-01672-1

Table 2.

Recent smartphone-based SPR sensors

No Principle Smartphone utilization Signal
modulation
Application/detection Performance Ref
1 LSPR Camera and LED Wavelength and intensity

Heart disease biomarker

Cardiac human troponin I

LOD: 50 ng/mL

Resolution: 0.386 nm/pixel

[64]
2 Camera Wavelength and intensity

Protein

Bovine serum albumin (BSA)

LOD: 19.2 μg/mL

Resolution: 0.336 nm/pixel

[65]
3 Camera Intensity Water pollutant NH3 LOD: 200 mg/L [66]
4 Camera Intensity Water pollutant Cr3+ LOD: 11 μM [67]
5 Camera Intensity Water pollutant Hg2+ LOD: 0.2 ppb [68]
6 Camera Intensity Water pollutant Cd2+ LOD: 1.12 µg/L [69]
7 Camera Wavelength and intensity Cancer biomarker CA13-5

LOD: 0.87 U/mL

Resolution: 0.71 nm

Sensitivity: 161 nm/RIU

[70]
8

Prism

coupled

Camera and

screen

Angle and

intensity

Cancer marker

β2 microglobulin (β2M)

LOD: 0.1 μg/mL

Resolution: 0.111 degree/pixel

Sensitivity: 11 × 10−3 RIU/degree

[71]
9

Prism

coupled

SPCE

Camera

Angle and

intensity

Antibiotic

Doxycycline

LOD: 22.5 aM [72]
10

Waveguide coupled

Fiber optic based

Camera and LED Wavelength and intensity Refractive index sensor Sensitivity: 5.96 × 10−4 RIU/pixel [73]
11 Camera and LED Intensity

Antibody in blood

Immunoglobulin G (IgG)

LOD: 47.4 nM [74]
12 Camera and LED Intensity

Antibody in blood

Immunoglobulin G (IgG)

LOD: 0.02 mg/mL

Resolution: 2.3 × 10−4 RIU

[75]
13 Camera and LED Wavelength and intensity Temperature sensor Sensitivity: 0.46 pixel/°C [76]
14 Waveguide coupled and LSPR Camera and LED Intensity Refractive index sensor

Resolution: 3.8 × 10−5 RIU

Sensitivity: 5.47/RIU

[77]
15 Grating coupled

Camera and

Screen

Angle and

intensity

Protein

Bovine serum albumin

Sensitivity 10−5 RIU/degree [78]
16 Camera and LED Wavelength and intensity

Endotoxin

Lipopolysaccharides

LOD: 32.5 ng/mL [79]
17 Camera Intensity

Antibody in blood

Mouse IgG

Resolution: 4.12 × 10−5 RIU [80]
18 Camera Intensity Refractive index sensor Sensitivity: 282/RIU [81]
19

Grating coupled

SPP-BW

Camera Intensity

Pesticide

Imidacloprid

LOD: 1 ppb [82]
20 Camera Intensity

Protein

Bovine serum albumin (BSA)

LOD: 0.001 mg/mL [83]
21 Camera Wavelength and intensity

Protein

Bovine serum albumin (BSA)

LOD 2.43 μg/ml

Resolution: 5.88 × 10−6 RIU

[84]