Table.
Baseline characteristics
| No incident dementia (n=198 272) | Incident dementia (n=4766) | ||
|---|---|---|---|
| Age, years | 64·9 (3·0) | 66·6 (2·8) | |
| Sex | |||
| Female | 105 017 (53·0%) | 2226 (46·7%) | |
| Male | 93 255 (47·0%) | 2540 (53·3%) | |
| Education* | |||
| Higher | 64 750 (32·7%) | 1198 (25·1%) | |
| Upper secondary | 14 361 (7·2%) | 352 (7·4%) | |
| Lower secondary | 17 880 (9·0%) | 397 (8·3%) | |
| Vocational | 46 240 (23·3%) | 929 (19·5%) | |
| Other | 55 041 (27·8) | 1890 (39·7) | |
| Socioeconomic status quintile† | |||
| 1 (least deprived) | 39 731 (20·0%) | 833 (17·5%) | |
| 2–4 | 119 043 (60·0%) | 2689 (56·4%) | |
| 5 (most deprived) | 39 335 (19·8%) | 1239 (26·0%) | |
| Other | 163 (0·1%) | 5 (0·1%) | |
| Cardiometabolic conditions | |||
| Stroke only | 3006 (1·5%) | 157 (3·3%) | |
| Diabetes only | 11 068 (5·6%) | 524 (11·0%) | |
| Myocardial infarction only | 5646 (2·8%) | 235 (4·9%) | |
| Stroke and myocardial infarction | 508 (0·3%) | 50 (1·0%) | |
| Stroke and diabetes | 598 (0·3%) | 66 (1·4%) | |
| Myocardial infarction and diabetes | 1372 (0·7%) | 107 (2·2%) | |
| Stroke and myocardial infarction and diabetes | 122 (0·1%) | 16 (0·3%) | |
| No cardiometabolic conditions | 176 318 (88·9%) | 3659 (76·8%) | |
| Number of cardiometabolic conditions‡ (cardiometabolic multimorbidity index) | |||
| 0 | 176 318 (88·9%) | 3659 (76·8%) | |
| 1 | 19 720 (9·9%) | 916 (19·2%) | |
| 2 | 2112 (1·1%) | 175 (3·7%) | |
| 3 | 122 (0·1%) | 16 (0·3%) | |
| Genetic risk category§ | |||
| Low | 39 879 (20·1%) | 729 (15·3%) | |
| Intermediate | 119 019 (60·0%) | 2803 (58·8%) | |
| High | 39 374 (19·9%) | 1234 (25·9%) | |
Data are mean (SD) or n (%). Percentages might not sum to 100 because of rounding.
Higher education is defined as college or university degree or other professional qualification; upper secondary as the second or final stage of secondary education; lower secondary as the first stage of secondary education; and vocational as work-related practical qualifications.
Socioeconomic status assessed with the Townsend deprivation index,21 which combines information on social class, employment, car availability, and housing.
Cardiometabolic multimorbidity index groups are mutually exclusive.
Genetic risk categories were defined according to a polygenic risk score as low (lowest quintile), intermediate (quintiles 2 to 4), or high (highest quintile).