Figure 3. Change in MRI-PDFF measured liver fat comparing exercise training to standard clinical care.
(A) No significant change was observed in MRI-PDFF in standard of care subjects. (B) MRI-PDFF significantly decreased following exercise training. (C) Exercise training decreased liver fat as measured by MRI-PDFF (−4.7 +/− 5.6 vs. 1.2 +/− 2.8% absolute liver fat, p=0.01). (D) 40% of exercise subjects had ≥30% relative reduction in MRI-PDFF, the threshold for histologic response, compared to 13% of standard of care subjects.