TABLE 3.
Quantitative results of HB-HTA of MP versus SCS (information is presented for items where qualitative information was available).
Dimension | Available information |
---|---|
Clinical | • No increased complication rate (15, 24, 30, 32, 35, 37) |
• Prolonged total graft preservation time (15, 35) | |
• 10–50% reduced risk for EAD (7, 17, 24, 30, 36, 37, 41, 47) | |
• 7–15% less IRI (7, 17, 28, 32, 39, 42) | |
• 7–50% fewer IBC (7, 15, 17, 24, 30, 31, 36, 37, 47) | |
• Comparable (22, 24) or improved 1-year graft (30, 47) and patient survival (30, 35) | |
• Up to a 50% lower discard rate (31, 35, 43) | |
Economic(al) | • Increased costs [per-run cost of 18,593.02 $Can (13); per-patient increase of 9,341£ (20)] |
• Theoretically improved cost-effectiveness and cost utility (21) | |
• Increased use of economic resources (13, 21) | |
Ethical | • Anecdotal single reports of MP-related adverse events (37) |
Social | • No difference in length of hospital stay (15, 24, 30) |
Note. EAD, early allograft dysfunction; HB-HTA, hospital-based health technology assessment; HT, health technology; HTA, health technology assessment; IBC, ischemic biliary complications; IRI, ischemia reperfusion injury; MP, machine perfusion; SCS, static cold storage.