Figure 1.

Prediction paradigms and resulting scenarios. For each paradigm, all patients included in the study were dichotomized: Paradigm I for favorable outcome with mRS 0–2 at 3 months (vs. the remaining 3–6) and paradigm II for poor outcome with mRS 5 and 6 (vs. the remaining 0–4). For the prediction scenarios, three sets of prediction variables A, B, and C were consecutively added. For an overview of prediction variables included in the sets, see Table 1. The combination of each of the three prediction variable sets and two prediction paradigms yielded six distinct scenarios.