Table 1.
Knock-in mice for analyzing XCR1+ DC.
| Targeted gene locus | Knocked-in gene | Purpose | Ref |
|---|---|---|---|
| Xcr1 | DTR Venus | Inducible ablation | (38) |
| Marking | |||
| cre | Gene deletion | (8, 39) | |
| cre, mCherry | Gene deletion | (40) | |
| Marking | |||
| cre, mTFP1 | Gene deletion | (41) | |
| Marking | |||
| Venus | Marking | (38) | |
| GFP | Marking | (42) | |
| KikGR | Marking | (43) | |
| (Photoconvertible) | |||
| Clec9a | DTR | Inducible ablation | (44)* |
| Cre | Gene deletion | (45) | |
| GFP | Marking | (46) | |
| Karma | DTR, tdTomato** | Inducible ablation | (47) |
| Marking | |||
| Cre | Gene deletion | (39) |
*This mutant was generated by transfection with a recombineered bacterial artificial chromosome (BAC) clone carrying DTR in the Clec9a locus.
**tdTomato represents the fluorescent tandem dimer Tomato.