Table 2.
Human orthologues among the 30 most abundant saliva miRNAs from uninfected Ae. aegypti.
| Ae. aegypti | sequence | H. sapiens | seed | mm | alignment |
|---|---|---|---|---|---|
| aae-miR-14-3p | TCAGTCTTTTTCTCTCTCCTAT | – | – | – | – |
| aae-miR-1891-2-5p | TGAGGAGTTAATTTGCGTGTTT | – | – | – | – |
| aae-miR-1-3p | TGGAATGTAAAGAAGTATGGAG | hsa-miR-1-3p | Y | 1 | 1–22/1–21 |
| aae-miR-276-1-3p | TAGGAACTTCATACCGTGCTC | – | – | – | – |
| aae-miR-263a-5p | AATGGCACTGGAAGAATTCACGG | hsa-miR-183-5p | Y | 1 | 2–21/2–21 |
| aae-miR-7-5p | TGGAAGACTAGTGATTTTGTTGT | hsa-miR-7-5p | Y | - | 1–23/1–23 |
| aae-miR-34-5p | TGGCAGTGTGGTTAGCTGGTTG | hsa-miR-34c-5p | Y | 2 | 2–22/2–22 |
| aae-miR-2940-3p | GTCGACAGGGAGATAAATCACT | – | – | – | – |
| aae-miR-317-1-3p | TGAACACAGCTGGTGGTATCT | – | – | – | – |
| aae-let-7-5p | TGAGGTAGTTGGTTGTATAGT | hsa-let-7a-5p | Y | 1 | 1–21/1–21 |
| aae-miR-263b-5p | CTTGGCACTGGGAGAATTCACAG | – | – | – | – |
| aae-miR-2940-5p | TGGTTTATCTTATCTGTCGAGGC | – | – | – | – |
| aae-miR-8-3p | TAATACTGTCAGGTAAAGATGTC | hsa-miR-141-3p | Y/N | 2 | 1–21/1–21 |
| aae-miR-184-3p | TGGACGGAGAACTGATAAGGGC | hsa-miR-184 | Y | – | – |
| aae-miR-281-3p | TGTCATGGAATTGCTCTCTTTA | – | – | – | – |
| aae-miR-100-5p | AACCCGTAGATCCGAACTTGTG | hsa-miR-100-5p | Y | - | 1–22/1–22 |
| aae-miR-281-5p | AAGAGAGCTATCCGTCGAC | – | – | – | – |
| aae-miR-279-3p | TGACTAGATCCACACTCATTAA | – | – | – | – |
| aae-miR-277-3p | TAAATGCACTATCTGGTACGAC | – | – | – | – |
| aae-bantam-3p | TGAGATCATTTTGAAAGCTGAT | – | – | – | – |
| aae-miR-87-3p | GTGAGCAAATTTTCAGGTGTGT | – | – | – | – |
| aae-miR-843a | GTCCTGTCACGGTCGCCA | – | – | – | – |
| aae-miR-970-3p | TCATAAGACACACGCGGCTAT | – | – | – | – |
| aae-miR-8-5p | CATCTTACCGGGCAGCATTAGA | hsa-miR-200b-5p | Y | 2 | 1–22/1–22 |
| aae-miR-9a-1-5p | TCTTTGGTTATCTAGCTGTATGA | hsa-miR-9-5p | Y | – | 1–23/1–23 |
| aae-miR-125-5p | TCCCTGAGACCCTAACTTGTGA | hsa-miR-125b-5p | Y | – | 1–22/1–22 |
| aae-miR-1889-5p | TAATCTCAAATTGTAACAGTGG | – | – | – | – |
| aae-miR-2945-3p | TGACTAGAGGCAGACTCGTTTA | – | – | – | – |
| aae-miR-252-5p | TAAGTACTAGTGCCGCAGGAG | – | – | – | – |
| aae-miR-275-3p | TCAGGTACCTGAAGTAGCGC | – | – | – | – |
Y, seed (nt 2–8) fully conserved; Y/N, seed partially conserved; mm, total number of mismatches in the aligned region. Aedes aegypti miRNAs with human orthologues are in bold.