Table 3.

Distribution in other species of Aedes aegypti saliva miRNAs found in this study.

Aedes aegypti	Homo sapiens	Anopheles coluzzii	Aedes aegypti	Aedes albopictus	Ixodes ricinus	Haemaph. longicornis	Brugia malayi	Heligmos. polygyrus
aae-miR-14-3p		√	√	√
aae-miR-1891-2-5p		√	√	√
aae-miR-1-3p		√			√	√	√	√
aae-miR-276-1-3p		√	√	√	√	√
aae-miR-263a-5p		√	√	√	√	√		√
aae-miR-7-5p		√			√	√	√
aae-miR-34-5p		√	√	√			√	√
aae-miR-2940-3p			√	√
aae-miR-317-1-3p		√	√	√	√
aae-let-7-5p	√	√	√	√	√	√	√	√
aae-miR-263b-5p		√
aae-miR-2940-5p			√	√
aae-miR-8-3p		√	√	√	√			√
aae-miR-184-3p		√	√	√		√
aae-miR-281-3p		√	√	√			√
aae-miR-100-5p		√	√	√	√	√	√	√
aae-miR-281-5p		√	√	√	√		√
aae-miR-279-3p		√	√	√	√		√	√
aae-miR-277-3p		√	√	√
aae-bantam-3p		√	√	√			√	√
aae-miR-87-3p			√			√	√	√
aae-miR-843a
aae-miR-970-3p			√	√
aae-miR-8-5p		√	√	√	√
aae-miR-9a-1-5p		√			√	√	√	√
aae-miR-125-5p		√	√	√	√			√
aae-miR-1889-5p			√		√
aae-miR-2945-3p		√						√
aae-miR-252-5p		√	√	√	√		√
aae-miR-275-3p		√	√	√	√	√
Total	1	24	24	22	16	10	12	12
Mimicking human		11	8	8	8	7	6	8

MicroRNAs homologous to the top 30 miRNAs found in the saliva of Aedes aegypti were searched among the top 50 in human saliva (Yeri et al., 2017), in the saliva of Anopheles coluzzii (Arcà et al., 2019), Aedes aegypti and Aedes albopictus (Maharaj et al., 2015), Ixodes ricinus (Hackenberg et al., 2017), Haemaphysalis longicornis (Malik et al., 2019) and among the top 50 exosomal miRNAs from Brugia malayi (Zamanian et al., 2015) and Heligmosomoides polygyrus (Buck et al., 2014). The total number of conserved miRNAs and of miRNA identical to human miRNAs are shown at the bottom. Aedes aegypti miRNAs identical (or almost identical) to human miRNAs are highlighted in bold.