Fig. 6. Central metabolism of C. albicans is altered by L. rhamnosus colonization.

Reactions associated to glycolysis, TCA cycle, oxidative phosphorylation are indicated, as well as relationships with additional metabolic pathways (pentose phosphate pathway, nitrogenated bases, sulfur metabolism, butanoate, propanoate, and pantothenate, CoA, β-Alanine and glutathione metabolism). Information on metabolome (12 h) and transcriptomic (24 h) data are combined with in silico genome-wide metabolic flux predictions (12 h). Dotted arrows represent several combined reactions. For the reaction abbreviations see Table S3.