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. 2022 Jun 9;13:3203. doi: 10.1038/s41467-022-30884-6

Table 2.

Main analysis; adjusted Third Dose Effectiveness (VE) against SARS-Cov2 infection.

Exposure Groups/Booster Period Cases Controls Adjusted Third Dose VE (%) for SARS-Cov2 Infection (CI 95%)
Aug. 2021 (−5)‡ 21,777 21,234 Reference
Sep. 2021 (−4)‡ 25,419 24,432 3.6 (0.6, 6.5)
Oct. 2021 (−3)‡ 7050 7773 16.5(13, 19.9)
Nov. 2021 (−2)‡ 792 1156 35.7(29.8, 41.2)
Dec. 2021 (−1)‡ 421 864 53.4(47.7, 58.6)
55459 55459

‡ Denotes the months prior to the outcome period. Therefore, those who received the booster in October 2021, received the third dose 3 months prior to the outcome period.

VE was defined as 100%*[1-(Odds Ratio)] for each of the month-since-vaccination categories.

ORs were estimated with conditional logistic regression on a 1:1 matched dataset, and adjusted for comorbidities.