Table 2.
Variants in PTBP2 looked up in GWAS datasets for BMI and AN.
| dbSNP_ID | MAa | BMIb | ANc | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Combined sexes | Female | Male | ||||||||
| Freq.d | betae | p valuef | beta | p value | beta | p value | beta | p value | ||
| rs190499333 | A | 0.007 | 0.015 | 3.04 × 10−1 | 0.026 | 1.98 × 10−1 | 0.0088 | 6.89 × 10−1 | NA | |
| rs182749916 | A | NAg | −0.121 | 2.82 × 10−6 | ||||||
| rs3748785 | A | 0.306 | −0.010 | 1.05 × 10−6 | −0.007 | 9.81 × 10−3 | −0.014 | 3.66 × 10−6 | −0.009 | 5.62 × 10−1 |
| rs3748784 | A | 0.486 | −0.009 | 3.09 × 10−6 | −0.005 | 5.84 × 10−2 | −0.013 | 4.03 × 10−6 | 0.012 | 3.81 × 10−1 |
| rs370506456 | A | 0.006 | 0.037 | 1.18 × 10−2 | 0.051 | 1.22 × 10−2 | 0.038 | 8.59 × 10−2 | NA | |
| rs3762411 | G | 0.485 | −0.010 | 2.90 × 10−8 | −0.007 | 3.86 × 10−3 | −0.013 | 3.84 × 10−7 | 0.013 | 3.41 × 10−1 |
| rs531865117 | C | 0.010 | −0.014 | 1.38 × 10−1 | −0.021 | 1.11 × 10−1 | 0.0004 | 9.76 × 10−1 | NA | |
| rs139414147 | G | 0.002 | −0.006 | 8.19 × 10−1 | −0.027 | 4.31 × 10−1 | 0.026 | 4.74 × 10−1 | NA | |
| rs12727525 | C | 0.332 | 0.014 | 2.33 × 10−12 | 0.011 | 1.37 × 10−4 | 0.019 | 1.64 × 10−10 | 0.060 | 4.22 × 10−5 |
| rs75437331 | G | 0.019 | 0.006 | 4.21 × 10−1 | 0.004 | 7.02 × 10−1 | −0.002 | 8.90 × 10−1 | 0.048 | 4.69 × 10−1 |
| rs273873 | T | 0.327 | 0.015 | 4.69 × 10−17 | 0.012 | 8.00 × 10−7 | 0.020 | 4.53 × 10−14 | NA | |
| rs188987764 | G | 0.002 | −0.009 | 7.46 × 10−1 | 0.015 | 6.97 × 10−1 | −0.06 | 1.29 × 10−1 | NA | |
| rs368216434 | G | 0.0005 | −0.051 | 2.35 × 10−1 | −0.075 | 2.00 × 10−1 | 0 | 9.96 × 10−1 | NA | |
| rs561340891 | Dh | NA | 0.006 | 9.36 × 10−1 | ||||||
| rs6699634 | C | 0.007 | 0.003 | 8.06 × 10−1 | 0.007 | 6.63 × 10−1 | 0.005 | 7.76 × 10−1 | NA | |
| rs563986850 | C | 0.0003 | −0.011 | 8.87 × 10−1 | −0.045 | 6.43 × 10−1 | −0.034 | 7.77 × 10−1 | NA | |
| rs6699932 | G | 0.191 | −0.006 | 5.58 × 10−3 | −0.006 | 4.12 × 10−2 | −0.008 | 1.84 × 10−2 | −0.066 | 1.37 × 10−4 |
| rs41299549 | C | 0.020 | 0.004 | 5.77 × 10−1 | 0.002 | 8.76 × 10−1 | −0.002 | 8.19 × 10−1 | 0.048 | 4.61 × 10−1 |
| rs189827209 | C | 0.003 | −0.036 | 6.57 × 10−2 | −0.023 | 4.02 × 10−1 | −0.046 | 1.16 × 10−1 | NA | |
| rs273886 | G | 0.481 | −0.009 | 3.31 × 10−6 | −0.005 | 4.09 × 10−2 | −0.013 | 7.44 × 10−6 | 0.014 | 3.04 × 10−1 |
aMA: minor allele (minor allele).
bBMI: data extracted from BMI GWAS summary statistics [11].
cAN: data extracted from AN GWAS summary statistics [10].
dFreq.: frequency of minor allele in BMI GWAS (combined sexes).
ebeta: effect size of minor allele.
fp value: p value extracted from corresponding database, the p values in bold were genome-wide significant.
gNA: not available.
hD: deletion.