Table 3.
Assessment of Z-scores from sex-stratified BMI GWAS.
Regions | annotation | |Z-score|b ≥ 2 | |Z-score| < 2 | The percentage of variants with a|Z-score| ≥ 2 (%)c |
---|---|---|---|---|
PTBP2 genomic region | all variants | 80 | 810 | 8.99 |
significant variantsa | 40 | 21 | 65.57 | |
PTBP2 ± ~1000 kb genomic region | all variants | 1064 | 20415 | 4.95 |
significant variants | 256 | 438 | 36.89 | |
PTBP2− ~1000 kb upstream genomic region | all variants | 720 | 10977 | 6.16 |
significant variants | 216 | 392 | 35.53 | |
PTBP2 + ~1000 kb downstream genomic region | all variants | 264 | 8628 | 2.97 |
significant variants | 0 | 25 | 0.00 |
asignificant variants: the variants with p value smaller than 5 × 10−8.
b|Z-score|: absolute value of Z-score.
cThe percentage of variants with a |Z-score| ≥ 2: the percentage of variants with a Z-score (absolute value) larger than 2.