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. 2022 Jun 9;13:3195. doi: 10.1038/s41467-022-30814-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Novel microfabrication techniques combined with creativity enable the production of different microfluidic tools that, in turn, facilitate the development of novel experimental paradigms to be used with small multicellular model organisms. Microfluidics empower researchers with tremendous control over sample stimulation while also enabling precise manipulation of samples, and being compatible with high-resolution live imaging. The potential of these microtechnologies is accelerating as they are integrated with additional technologies, become more accessible, and are designed to be multifunctional. Figure created with BioRender.com.