Table 6.
Interobserver and intraobserver agreement using the Sorensen-Dice similarity coefficient in expert segmentations of the cup and optic disc in retinal fundus images (second and third columns).
| Dice similarity coefficient | Difference of area-based CDR | ||||
|---|---|---|---|---|---|
| Optic cup | Optic disc | mean ± std | p-value | CI | |
| Interobserver | 0.823 ± 0.089 | 0.935 ± 0.036 | −0.002 ± 0.045 | 0.231 | [−0.006, 0.001] |
| Intraobserver | |||||
| • Expert #1 | 0.827 ± 0.093 | 0.958 ± 0.037 | 0.002 ± 0.055 | 0.803 | [−0.018, 0.023] |
| • Expert #2 | 0.834 ± 0.099 | 0.955 ± 0.033 | 0.008 ± 0.060 | 0.465 | [−0.014, 0.030] |
Statistical characterization of the interobserver and intraobserver variability using the difference in area-based CDR using the segmentations of the experts (forth to sixth columns).