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. 2022 May 27;9:874916. doi: 10.3389/fmed.2022.874916

Table 1.

Comparison of HK-2 cell ultrastructure in different experimental groups.

Control group 15 mmol/L group 30 mmol/L group 45 mmol/L group
Cell morphology Normal Slight swelling Significant swelling Significant swelling
Cell membrane Intact and continuous Partial membranous perforation and cytoplasmic content overflow Membranous perforation and massive cytoplasm content overflow Intact and continuous
Cytoplasm The organelle structure was intact without damage Vesiculation and expansion of endoplasmic reticulum Vesiculation and expansion of endoplasmic reticulum, mitochondrial vacuolation, and Golgi swelling Mitochondrial vacuolation and myeloid structure
Nucleus No chromatin pyknosis or adherence to nuclear membrane Partial nuclear chromatin pyknosis, margination and adhesion to the nuclear membrane Disappearance of part of nucleoli, chromatin margination and adhesion to the nuclear membrane No chromatin margination or adhesion to the nuclear membrane