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. 2022 Jun 10;23:152. doi: 10.1186/s12931-022-02074-x

Table 2.

Reasons to include the patient in the system

Argentina (n = 2491) Brazil (n = 2620) Chile (n = 3352) Colombia (n = 2057) LATAM (n = 10,520) Spain (n = 18,272) Turkey (n = 2035) Total (n = 30,827)
COPD 1234 (49.5) 1909 (72.9) 1189 (35.5) 1936 (94.1) 6268 (59.6) 7025 (38.4) 1936 (95.1) 15,230 (49.4)
Poorly controlled asthma 682 (27.4) 183 (7.0) 325 (9.7) 61 (3.0) 1251 (11.9) 2095 (11.5) 35 (1.7) 3381 (11.0)
Bronchiectasis 127 (5.1) 267 (10.2) 155 (4.6) 76 (3.7) 625 (5.9) 777 (4.3) 33 (1.6) 1435 (4.7)
Serum AAT concentration level below the limit of normality 0 (0.0) 34 (1.3) 2 (0.1) 0 (0.0) 36 (0.3) 321 (1.8) 0 (0.0) 357 (1.2)
Blood relatives of individuals with AATD 2 (0.1) 176 (6.7) 11 (0.3) 0 (0.0) 189 (1.8) 548 (3.0) 28 (1.4) 765 (2.5)
Spouses of individuals with AATD 0 (0.0) 8 (0.3) 1 (0.0) 0 (0.0) 9 (0.1) 21 (0.1) 0 (0.0) 30 (0.1)
Hepatopathy of unknown cause 6 (0.2) 79 (3.0) 6 (0.2) 0 (0.0) 91 (0.9) 200 (1.1) 3 (0.1) 294 (1.0)
Dyspnea and chronic cough in many family members 272 (10.9) 39 (1.5) 93 (2.8) 0 (0.0) 404 (3.8) 368 (2.0) 7 (0.3) 779 (2.5)
Decreased or lack of peak alpha-1 protein on proteinogram 3 (0.1) 17 (0.6) 3 (0.1) 1 (0.0) 24 (0.2) 551 (3.0) 2 (0.1) 577 (1.9)
Panniculitis or multiorgan vasculitis of unknown cause 8 (0.3) 14 (0.5) 2 (0.1) 0 (0.0) 24 (0.2) 16 (0.1) 1 (0.0) 41 (0.1)
SARS-CoV-2 infection 4 (0.2) 28 (1.1) 190 (5.7) 0 (0.0) 222 (2.1) 1262 (6.9) 0 (0.0) 1484 (4.8)
None of the above 191 (7.7) 85 (3.2) 1453 (43.3) 27 (1.3) 1756 (16.7) 5937 (32.5) 8 (0.4) 7701 (25.0)

Data expressed as absolute (relative) frequencies. Percentages referred to the total number per country