Table 4.

Distribution of frequent genotypes according to the background disease an geographical areas

Diseases	Frequent genotypes	Argentina	Brazil	Chile	Colombia	LATAM	Spain	Turkey	Total
COPD	n	1234	1909	1189	1936	6268	7025	1936	15,229
	MS	126 (10.2)	249 (13.0)	100 (8.4)	185 (9.6)	660 (10.5)	1337 (19.0)	7 (0.4)	2004 (13.2)
	MZ	35 (2.8)	83 (4.3)	13 (1.1)	13 (1.1)	153 (2.4)	483 (6.9)	34 (1.8)	670 (4.4)
	SS	7 (0.6)	15 (0.8)	2 (0.2)	2 (0.2)	32 (0.5)	180 (2.6)	0 (0)	212 (1.4)
	SZ	5 (0.4)	13 (0.7)	1 (0.1)	1 (0.1)	24 (0.4)	140 (2.0)	0 (0)	164 (1.1)
	ZZ	4 (0.3)	42 (2.2)	2 (0.2)	2 (0.1)	52 (0.8)	74 (1.1)	6 (0.3)	132 (0.9)
Poorly controlled asthma	n	682	183	325	61	1251	2095	35	3381
	MS	62 (9.1)	20 (10.9)	28 (8.6)	5 (8.2)	115 (9.2)	409 (19.5)	0 (0)	524 (15.5)
	MZ	15 (2.2)	9 (4.9)	4 (1.2)	1 (1.6)	29 (2.3)	155 (7.4)	1 (2.9)	185 (5.5)
	SS	2 (0.3)	2 (1.1)	1 (0.3)	0 (0)	5 (0.4)	65 (3.1)	0 (0)	70 (2.1)
	SZ	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	37 (1.8)	0 (0)	37 (1.1)
	ZZ	0 (0)	1 (0.5)	0 (0)	1 (1.6)	2 (0.2)	19 (0.9)	1 (2.9)	22 (0.7)
Bronchiectasis	n	127	267	155	76	625	777	33	1435
	MS	5 (3.9)	39 (14.6)	16 (10.3)	7 (9.2)	67 (10.7)	154 (19.8)	0 (0)	221 (15.4)
	MZ	7 (5.5)	11 (4.1)	2 (1.3)	0 (0)	20 (3.2)	81 (10.4)	1 (3.0)	102 (7.1)
	SS	0 (0)	5 (1.9)	1 (0.6)	0 (0)	6 (1.0)	36 (4.6)	0 (0)	42 (2.9)
	SZ	0 (0)	4 (1.5)	0 (0)	0 (0)	4 (0.6)	22 (2.8)	0 (0)	26 (1.8)
	ZZ	0 (0)	9 (3.4)	0 (0)	0 (0)	9 (1.4)	18 (2.3)	0 (0)	27 (1.9)
Panniculitis or multiorgan vasculitis of unknown cause	n	8	14	0	0	22	16	1	41
	MS	1 (12.5)	2 (14.3)	0 (0)	0 (0)	3 (12.5)	3 (18.8)	0 (0)	6 (14.6)
	MZ	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	1 (6.3)	0 (0)	1 (2.4)
	SS	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)
	SZ	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)
	ZZ	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)

Data expressed as absolute numbers with percentages in parenthesis; showing percentages referred to the total number of samples in the geographical area with that particular disease