Table 5.
Infection risk by stage and prevention strategy for heterosexual males
| HET male | No prevention | Condom | Ag/Ab RDT | PCR RDT |
|---|---|---|---|---|
| Stage 1 | 4.5 × 10−11 (3.2 × 10−11, 6.3 × 10−11) | 9.1 × 10−12 (1.8 × 10−12, 4.1 × 10−11) | 4.5 × 10−11 (3.2 × 10−11, 6.3 × 10−11) | 1.4 × 10−12 (9.7 × 10−13, 1.9 × 10−12) |
| Stage 2 | 3.2 × 10−10 (2.4 × 10−10, 4.0 × 10−10) | 6.3 × 10−11 (1.4 × 10−11, 2.6 × 10−10) | 2.8 × 10−10 (2.1 × 10−10, 3.5 × 10−10) | 9.5 × 10−12 (7.2 × 10−12, 1.2 × 10−11) |
| Stage 3 | 1.9 × 10−10 (1.4 × 10−10, 2.4 × 10−10) | 3.8 × 10−11 (8.4 × 10−12, 1.6 × 10−10) | 1.7 × 10−10 (1.3 × 10−10, 2.1 × 10−10) | 5.7 × 10−12 (4.3 × 10−12, 7.2 × 10−12) |
| Stage 4 | 2.8 × 10−10 (2.3 × 10−10, 3.3 × 10−10) | 5.5 × 10−11 (1.3 × 10−11, 2.2 × 10−10) | 2.4 × 10−10 (2.0 × 10−10, 2.9 × 10−10) | 8.3 × 10−12 (6.8 × 10−12, 10.0 × 10−12) |
| Stage 5 | 1.5 × 10−9 (1.4 × 10−9, 1.6 × 10−9) | 2.9 × 10−10 (8.0 × 10−11, 1.0 × 10−9) | 2.4 × 10−10 (2.6 × 10−9, 2.5 × 10−10) | 4.4 × 10−11 (4.2 × 10−11, 4.7 × 10−11) |
| Chronic stage | 9.5 × 10−8 (9.5 × 10−8, 9.5 × 10−8) | 1.9 × 10−8 (5.5 × 10−9, 6.1 × 10−8) | 2.6 × 10−9 (2.6 × 10−9, 2.6 × 10−9) | 2.8 × 10−10 (2.8 × 10−10, 2.8 × 10−10) |
| Treatment stage | 1.0 × 10−8 (4.1 × 10−9, 2.8 × 10−8) | 2.1 × 10−9 (2.4 × 10−10, 1.8 × 10−8) | 2.8 × 10−10 (1.1 × 10−10, 7.5 × 10−10) | 1.0 × 10−8 (4.1 × 10−9, 2.8 × 10−8) |
| Overall | 1.1 × 10−7 (1.0 × 10−7, 1.2 × 10−7) | 2.1 × 10−8 (5.8 × 10−9, 8.1 × 10−8) | 3.8 × 10−9 (3.5 × 10−9, 4.5 × 10−9) | 1.3 × 10−8 (7.0 × 10−9, 3.1 × 10−8) |
| Overall (PrEP) | 1.5 × 10−8 (4.0 × 10−9, 4.5 × 10−8) | 3.0 × 10−9 (2.3 × 10−10, 2.9 × 10−8) | 5.3 × 10−10 (1.4 × 10−10, 1.6 × 10−9) | 1.8 × 10−9 (2.8 × 10−10, 1.1 × 10−8) |
HET, heterosexual.