Table 1.
Baseline characteristics of patients with non-muscular invasive bladder cancer (NMIBC) and non-metastatic muscle invasive bladder cancer (non-MMIBC)
| Variables | Total | <1 year | 1-3 years | 3-5 years | 5-10 years | >10 year | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| Patients | Deaths | SMR | Patients | Deaths | SMR | Patients | Deaths | SMR | Patients | Deaths | SMR | Patients | Deaths | SMR | Patients | Deaths | SMR | |
| NMIBC | ||||||||||||||||||
| Total | 111784 | 44638 | 1.40# (1.38/1.41) | 111784 | 5230 | 1.45# (1.41/1.49) | 106181 | 11700 | 1.43# (1.4/1.45) | 93500 | 9802 | 1.40# (1.38/1.43) | 68316 | 14117 | 1.36# (1.34-1.38) | 24255 | 3789 | 1.36# (1.31-1.4) |
| Age | ||||||||||||||||||
| 15-54 years | 12617 | 1394 | 2.03# (1.93-2.14) | 12617 | 110 | 2.36# (1.94-2.85) | 12431 | 314 | 2.54# (2.27-2.84) | 11931 | 269 | 2.14# (1.9-2.42) | 9850 | 502 | 1.85# (1.69-2.02) | 4804 | 199 | 1.67# (1.45-1.92) |
| 55-64 years | 24077 | 4840 | 1.73# (1.68-1.78) | 24077 | 387 | 1.80# (1.63-1.99) | 23590 | 1079 | 1.94# (1.83-2.06) | 22251 | 1023 | 1.88# (1.77-2) | 17429 | 1764 | 1.66# (1.58-1.74) | 7372 | 587 | 1.40# (1.29-1.51) |
| 65-74 years | 33685 | 11588 | 1.50# (1.47-1.53) | 33685 | 957 | 1.50# (1.4-1.59) | 32644 | 2645 | 1.62# (1.56-1.69) | 29747 | 2511 | 1.62# (1.55-1.68) | 21895 | 4101 | 1.45# (1.4-1.49) | 7561 | 1374 | 1.28# (1.21-1.35) |
| 75-84 years | 29770 | 17497 | 1.20# (1.18-1.21) | 29770 | 1969 | 1.40# (1.33-1.46) | 27718 | 4514 | 1.27# (1.23-1.31) | 22996 | 3849 | 1.14# (1.11-1.18) | 15699 | 5740 | 1.11# (1.08-1.14) | 4137 | 1425 | 1.29# (1.22-1.36) |
| 85+ years | 11621 | 9319 | 1.52# (1.49-1.55) | 11621 | 1807 | 1.40# (1.34-1.47) | 9784 | 3148 | 1.35# (1.3-1.4) | 6562 | 2150 | 1.55# (1.49-1.62) | 3431 | 2010 | 1.93# (1.84-2.01) | 376 | 204 | 2.97# (2.58-3.41) |
| Sex | ||||||||||||||||||
| Male | 86021 | 34976 | 1.39# (1.38-1.4) | 86021 | 3855 | 1.34# (1.3-1.39) | 81904 | 9224 | 1.41# (1.39-1.44) | 71967 | 7894 | 1.43# (1.4-1.46) | 52204 | 11098 | 1.37# (1.34-1.4) | 18341 | 2905 | 1.34# (1.29-1.39) |
| Female | 25763 | 9662 | 1.42# (1.39-1.45) | 25763 | 1375 | 1.87# (1.77-1.97) | 24277 | 2476 | 1.48# (1.42-1.54) | 21533 | 1908 | 1.30# (1.24-1.36) | 16112 | 3019 | 1.33# (1.28-1.37) | 5914 | 884 | 1.41# (1.32-1.5) |
| Race | ||||||||||||||||||
| White | 101420 | 40699 | 1.37# (1.36-1.38) | 101420 | 4644 | 1.39# (1.35-1.43) | 96470 | 10617 | 1.40# (1.37-1.42) | 85023 | 8953 | 1.38# (1.35-1.41) | 62291 | 12998 | 1.34# (1.32-1.37) | 22171 | 3487 | 1.34# (1.3-1.39) |
| Black | 5440 | 2320 | 1.72# (1.65-1.79) | 5440 | 373 | 2.27# (2.04-2.51) | 5042 | 654 | 1.82# (1.68-1.96) | 4339 | 497 | 1.70# (1.56-1.86) | 3078 | 624 | 1.48# (1.37-1.61) | 1052 | 172 | 1.54# (1.32-1.79) |
| 274 | 111 | 3.60# (2.96-4.33) | 274 | 18 | 4.71# (2.79-7.44) | 255 | 25 | 2.93# (1.9-4.32) | 223 | 26 | 4.22# (2.76-6.19) | 148 | 30 | 3.12# (2.11-4.46) | 53 | 12 | 4.40# (2.27-7.68) | |
| Asian or Pacific Islander | 4650 | 1508 | 1.72# (1.63-1.81) | 4650 | 195 | 1.97# (1.7-2.26) | 4414 | 404 | 1.79# (1.62-1.97) | 3915 | 326 | 1.69# (1.51-1.89) | 2799 | 465 | 1.66# (1.51-1.81) | 979 | 118 | 1.50# (1.24-1.79) |
| Differentiation | ||||||||||||||||||
| Grade I | 17233 | 6102 | 1.20# (1.17-1.24) | 17233 | 505 | 1.02 (0.93-1.11) | 16657 | 1367 | 1.16# (1.1-1.23) | 15161 | 1315 | 1.21# (1.15-1.28) | 12187 | 2182 | 1.25# (1.2-1.3) | 4981 | 733 | 1.31# (1.21-1.41) |
| Grade II | 33904 | 12445 | 1.22# (1.2-1.25) | 33904 | 1069 | 1.06 (1-1.13) | 32737 | 2721 | 1.14# (1.1-1.18) | 29730 | 2625 | 1.25# (1.21-1.3) | 21816 | 4527 | 1.27# (1.24-1.31) | 9767 | 1503 | 1.34# (1.28-1.41) |
| Grade III | 14851 | 7448 | 1.60# (1.56-1.64) | 14851 | 1044 | 1.96# (1.84-2.08) | 13757 | 1989 | 1.71# (1.63-1.78) | 11682 | 1492 | 1.49# (1.42-1.57) | 9074 | 2280 | 1.51# (1.44-1.57) | 3553 | 643 | 1.45# (1.34-1.56) |
| Grade IV | 23627 | 10430 | 1.67# (1.64-1.71) | 23627 | 1525 | 1.82# (1.73-1.91) | 22013 | 3318 | 1.82# (1.76-1.88) | 18446 | 2378 | 1.71# (1.64-1.78) | 11443 | 2666 | 1.48# (1.43-1.54) | 3359 | 543 | 1.41# (1.29-1.53) |
| T stage | ||||||||||||||||||
| Ta | 71504 | 25213 | 1.21# (1.19-1.22) | 71504 | 2154 | 0.97 (0.93-1.01) | 69140 | 6022 | 1.15# (1.12-1.18) | 62475 | 5701 | 1.24# (1.21-1.27) | 46328 | 8868 | 1.27# (1.25-1.3) | 16766 | 2468 | 1.30# (1.25-1.35) |
| Tis | 7385 | 3205 | 1.37# (1.33-1.42) | 7385 | 315 | 1.26# (1.13-1.41) | 7046 | 780 | 1.36# (1.26-1.45) | 6215 | 706 | 1.42# (1.32-1.53) | 4634 | 1107 | 1.41# (1.33-1.49) | 1753 | 297 | 1.31# (1.16-1.46) |
| T1 | 31804 | 15561 | 1.84# (1.81-1.86) | 31804 | 2524 | 2.31# (2.22-2.4) | 29146 | 4707 | 2.03# (1.97-2.09) | 24159 | 3289 | 1.78# (1.72-1.85) | 16920 | 4043 | 1.57# (1.53-1.62) | 5608 | 998 | 1.53# (1.43-1.62) |
| Pathology | ||||||||||||||||||
| Papillary transitional cell carcinoma | 92360 | 35229 | 1.32# (1.3-1.33) | 92360 | 3451 | 1.17# (1.13-1.21) | 88603 | 8967 | 1.32# (1.29-1.34) | 78818 | 7911 | 1.35# (1.32-1.38) | 57931 | 11690 | 1.33# (1.31-1.36) | 20886 | 3210 | 1.35# (1.3-1.39) |
| Transitional cell carcinoma | 16766 | 7949 | 1.76# (1.72-1.79) | 16766 | 1307 | 2.29# (2.17-2.42) | 15409 | 2352 | 1.93# (1.85-2.01) | 12913 | 1681 | 1.70# (1.62-1.78) | 9081 | 2110 | 1.51# (1.44-1.57) | 2881 | 499 | 1.43# (1.31-1.56) |
| Papillary carcinoma | 527 | 234 | 1.40# (1.22-1.59) | 527 | 24 | 1.46 (0.93-2.17) | 502 | 57 | 1.53# (1.16-1.98) | 443 | 38 | 1.19 (0.84-1.64) | 354 | 82 | 1.37# (1.09-1.7) | 181 | 33 | 1.50# (1.03-2.1) |
| Squamous cell carcinoma | 185 | 146 | 5.04# (4.26-5.93) | 185 | 76 | 14.33# (11.29-17.94) | 107 | 36 | 4.52# (3.17-6.26) | 69 | 14 | 2.52# (1.38-4.23) | 46 | 16 | 2.17# (1.24-3.52) | 14 | 4 | 1.46 (0.4-3.75) |
| Adenocarcinoma | 183 | 95 | 2.48# (2-3.03) | 183 | 26 | 4.77# (3.12-6.99) | 155 | 23 | 2.24# (1.42-3.37) | 132 | 25 | 3.33# (2.16-4.92) | 92 | 17 | 1.44 (0.84-2.31) | 26 | 4 | 1.18 (0.32-3.01) |
| Surgery | ||||||||||||||||||
| Local tumor excision | 102721 | 40681 | 1.37# (1.36-1.39) | 102721 | 4424 | 1.33# (1.29-1.37) | 97966 | 10690 | 1.41# (1.38-1.43) | 86393 | 8986 | 1.39# (1.36-1.42) | 63073 | 13046 | 1.36# (1.33-1.38) | 22486 | 3535 | 1.36# (1.32-1.41) |
| Cystectomy | 2428 | 947 | 1.72# (1.62-1.84) | 2428 | 127 | 2.26# (1.88-2.69) | 2286 | 232 | 1.78# (1.56-2.02) | 2027 | 207 | 1.74# (1.51-1.99) | 1502 | 312 | 1.64# (1.46-1.83) | 508 | 69 | 1.30# (1.01-1.65) |
| other | 6635 | 3010 | 1.66# (1.6-1.72) | 6635 | 679 | 3.02# (2.8-3.26) | 5929 | 778 | 1.65# (1.53-1.77) | 5080 | 609 | 1.55# (1.43-1.68) | 3741 | 759 | 1.30# (1.21-1.4) | 1261 | 185 | 1.32# (1.14-1.52) |
| Chemotherapy | ||||||||||||||||||
| Yes | 16762 | 5397 | 1.38# (1.34-1.41) | 16762 | 556 | 1.13# (1.04-1.22) | 16145 | 1650 | 1.42# (1.36-1.49) | 14317 | 1335 | 1.40# (1.33-1.48) | 9154 | 1579 | 1.40# (1.34-1.47) | 2120 | 277 | 1.43# (1.26-1.6) |
| No/Unknown | 95022 | 39241 | 1.40# (1.39-1.41) | 95022 | 4674 | 1.50# (1.46-1.55) | 90036 | 10050 | 1.43# (1.4-1.46) | 79183 | 8467 | 1.40# (1.37-1.43) | 59162 | 12538 | 1.35# (1.33-1.38) | 22135 | 3512 | 1.35# (1.31-1.4) |
| Radiation | ||||||||||||||||||
| yes | 111006 | 43999 | 1.38# (1.37-1.4) | 111006 | 5037 | 1.41# (1.37-1.45) | 105599 | 11465 | 1.41# (1.38-1.43) | 93155 | 9698 | 1.40# (1.37-1.42) | 68114 | 14026 | 1.36# (1.33-1.38) | 24200 | 3773 | 1.36# (1.31-1.4) |
| No/Unknown | 778 | 639 | 3.68# (3.4-3.98) | 778 | 193 | 5.23# (4.52-6.02) | 582 | 235 | 4.10# (3.59-4.66) | 345 | 104 | 3.04# (2.48-3.68) | 202 | 91 | 2.38# (1.92-2.92) | 55 | 16 | 2.34# (1.34-3.8) |
| non-MMIBC | ||||||||||||||||||
| Total | 26546 | 18829 | 4.67# (4.6-4.73) | 26546 | 7309 | 9.62# (9.4-9.84) | 19096 | 6948 | 6.07# (5.93-6.21) | 11935 | 2159 | 2.72# (2.61-2.84) | 7808 | 1970 | 1.85# (1.77-1.93) | 2511 | 443 | 1.64# (1.49-1.8) |
| Age | ||||||||||||||||||
| 15-54 years | 2535 | 1331 | 15.54# (14.72-16.4) | 2535 | 410 | 44.62# (40.4-49.15) | 2116 | 593 | 32.27# (29.73-34.98) | 1485 | 170 | 10.96# (9.38-12.74) | 1086 | 126 | 4.20# (3.5-5) | 491 | 32 | 2.54# (1.74-3.59) |
| 55-64 years | 5496 | 3166 | 8.56# (8.26-8.86) | 5496 | 975 | 21.73# (20.38-23.13) | 4482 | 1379 | 16.01# (15.17-16.88) | 3046 | 379 | 5.35# (4.82-5.91) | 2175 | 342 | 2.75# (2.46-3.05) | 811 | 91 | 2.09# (1.68-2.57) |
| 65-74 years | 7542 | 4984 | 5.21# (5.06-5.35) | 7542 | 1652 | 13.00# (12.38-13.65) | 5849 | 1924 | 8.13# (7.77-8.5) | 3870 | 631 | 3.37# (3.11-3.65) | 2510 | 621 | 2.05# (1.89-2.22) | 777 | 156 | 1.50# (1.28-1.76) |
| 75-84 years | 7463 | 6078 | 3.43# (3.34-3.51) | 7463 | 2539 | 8.78# (8.44-9.13) | 4889 | 2041 | 4.17# (3.99-4.35) | 2802 | 678 | 1.79# (1.66-1.93) | 1713 | 682 | 1.33# (1.23-1.43) | 391 | 138 | 1.33# (1.12-1.58) |
| 85+ years | 3510 | 3270 | 3.85# (3.72-3.99) | 3510 | 1733 | 5.98# (5.7-6.27) | 1760 | 1011 | 3.22# (3.02-3.42) | 732 | 301 | 2.12# (1.89-2.37) | 324 | 199 | 2.07# (1.79-2.38) | 41 | 26 | 3.79# (2.48-5.55) |
| Sex | ||||||||||||||||||
| Male | 19317 | 13457 | 4.36# (4.29-4.44) | 19317 | 4872 | 8.57# (8.33-8.81) | 14353 | 5123 | 5.82# (5.67-5.99) | 9068 | 1619 | 2.65# (2.53-2.79) | 5958 | 1504 | 1.84# (1.75-1.93) | 1918 | 339 | 1.63# (1.46-1.81) |
| Female | 7229 | 5372 | 5.65# (5.5-5.81) | 7229 | 2437 | 12.74# (12.24-13.26) | 4743 | 1825 | 6.87# (6.56-7.2) | 2867 | 540 | 2.94# (2.7-3.2) | 1850 | 466 | 1.88# (1.71-2.06) | 593 | 104 | 1.67# (1.37-2.03) |
| Race | ||||||||||||||||||
| White | 23280 | 16527 | 4.50# (4.43-4.57) | 23280 | 6381 | 9.27# (9.05-9.5) | 16805 | 6047 | 5.81# (5.67-5.96) | 10581 | 1921 | 2.66# (2.54-2.78) | 6924 | 1783 | 1.83# (1.74-1.91) | 2220 | 395 | 1.60# (1.45-1.77) |
| Black | 1961 | 1503 | 6.63# (6.3-6.98) | 1961 | 629 | 13.42# (12.39-14.51) | 1319 | 585 | 8.63# (7.94-9.36) | 723 | 141 | 3.16# (2.66-3.73) | 465 | 120 | 2.25# (1.86-2.69) | 135 | 28 | 2.02# (1.34-2.92) |
| American Indian-Alaska Native | 106 | 76 | 15.66# (12.34-19.6) | 106 | 35 | 26.84# (18.69-37.32) | 70 | 29 | 17.21# (11.52-24.71) | 40 | 6 | 7.25# (2.66-15.77) | 24 | 6 | 6.34# (2.33-13.79) | 9 | 0 | 0 (0-41.37) |
| Asian or Pacific Islander | 1199 | 723 | 5.55# (5.16-5.97) | 1199 | 264 | 11.19# (9.88-12.63) | 902 | 287 | 8.20# (7.28-9.21) | 591 | 91 | 3.59# (2.89-4.41) | 395 | 61 | 1.66# (1.27-2.14) | 147 | 20 | 2.09# (1.27-3.22) |
| Differentiation | ||||||||||||||||||
| Grade I | 316 | 196 | 3.05# (2.64-3.51) | 316 | 66 | 8.11# (6.27-10.32) | 247 | 58 | 3.86# (2.93-4.99) | 187 | 20 | 1.5 (0.92-2.32) | 146 | 41 | 1.89# (1.35-2.56) | 50 | 11 | 1.83 (0.91-3.27) |
| Grade II | 1473 | 1007 | 4.09# (3.84-4.35) | 1473 | 362 | 9.44# (8.5-10.47) | 1102 | 313 | 4.84# (4.32-5.41) | 775 | 145 | 2.99# (2.52-3.52) | 546 | 152 | 2.13# (1.8-2.49) | 197 | 35 | 1.51# (1.05-2.1) |
| Grade III | 8222 | 6220 | 4.71# (4.59-4.83) | 8222 | 2410 | 10.06# (9.66-10.47) | 5768 | 2252 | 6.46# (6.19-6.73) | 3456 | 663 | 2.66# (2.46-2.87) | 2486 | 706 | 1.87# (1.74-2.02) | 977 | 189 | 1.77# (1.53-2.04) |
| Grade IV | 14765 | 10146 | 4.67# (4.58-4.76) | 14765 | 3886 | 9.21# (8.92-9.5) | 10809 | 3889 | 6.05# (5.86-6.24) | 6802 | 1199 | 2.76# (2.61-2.92) | 4188 | 982 | 1.80# (1.69-1.91) | 1199 | 190 | 1.51# (1.3-1.74) |
| T | ||||||||||||||||||
| T2a | 4651 | 2918 | 3.57# (3.44-3.7) | 4651 | 962 | 6.52# (6.11-6.94) | 3673 | 1067 | 4.36# (4.1-4.63) | 2562 | 411 | 2.38# (2.15-2.62) | 1685 | 386 | 1.86# (1.68-2.06) | 444 | 92 | 2.01# (1.62-2.47) |
| T2b | 3899 | 2622 | 4.08# (3.93-4.24) | 3899 | 960 | 8.49# (7.96-9.05) | 2911 | 959 | 5.67# (5.31-6.04) | 1908 | 312 | 2.51# (2.24-2.81) | 1325 | 304 | 1.67# (1.49-1.87) | 486 | 87 | 1.62# (1.3-2) |
| T3a | 3016 | 2116 | 5.01# (4.8-5.23) | 3016 | 666 | 9.65# (8.93-10.41) | 2340 | 894 | 7.90# (7.39-8.44) | 1426 | 257 | 2.98# (2.63-3.37) | 939 | 249 | 2.01# (1.77-2.28) | 288 | 50 | 1.63# (1.21-2.15) |
| T3b | 1552 | 1163 | 6.48# (6.12-6.87) | 1552 | 463 | 13.38# (12.19-14.66) | 1084 | 494 | 10.17# (9.29-11.11) | 581 | 90 | 2.63# (2.11-3.23) | 371 | 97 | 1.92# (1.55-2.34) | 102 | 19 | 1.68# (1.01-2.62) |
| T4a | 3076 | 2514 | 7.19# (6.92-7.48) | 3076 | 1106 | 14.83# (13.97-15.73) | 1950 | 931 | 9.28# (8.69-9.89) | 1002 | 258 | 3.92# (3.46-4.43) | 615 | 188 | 2.16# (1.87-2.5) | 216 | 31 | 1.42 (0.96-2.01) |
| T4b | 655 | 599 | 24.19# (22.29-26.21) | 655 | 396 | 42.31# (38.24-46.69) | 252 | 167 | 23.93# (20.43-27.84) | 81 | 22 | 6.85# (4.29-10.36) | 50 | 13 | 3.23# (1.72-5.53) | 19 | 1 | 0.84 (0.02-4.71) |
| N | ||||||||||||||||||
| N0 | 22110 | 15233 | 4.17# (4.1-4.23) | 22110 | 5827 | 8.69# (8.47-8.92) | 16166 | 5371 | 5.19# (5.05-5.33) | 10613 | 1844 | 2.54# (2.43-2.66) | 7033 | 1782 | 1.82# (1.74-1.91) | 2248 | 409 | 1.66# (1.5-1.83) |
| N1 | 2066 | 1605 | 8.52# (8.11-8.95) | 2066 | 608 | 15.56# (14.35-16.85) | 1450 | 715 | 13.52# (12.55-14.55) | 720 | 164 | 4.80# (4.09-5.59) | 440 | 101 | 2.09# (1.71-2.55) | 160 | 17 | 1.21 (0.71-1.94) |
| N2 | 1823 | 1527 | 12.51# (11.89-13.15) | 1823 | 645 | 19.95# (18.44-21.55) | 1168 | 704 | 20.00# (18.55-21.53) | 449 | 114 | 5.37# (4.43-6.45) | 245 | 56 | 2.07# (1.57-2.69) | 70 | 8 | 1.27 (0.55-2.5) |
| N3 | 69 | 62 | 14.70# (11.27-18.85) | 69 | 29 | 22.08# (14.79-31.71) | 40 | 26 | 17.87# (11.67-26.18) | 14 | 5 | 6.39# (2.07-14.91) | 3 | 2 | 3 (0.36-10.85) | 0 | 0 | 0 (0-0) |
| Pathology | ||||||||||||||||||
| Transitional cell carcinoma | 14794 | 10692 | 5.02# (4.93-5.12) | 14794 | 4321 | 10.29# (9.99-10.6) | 10400 | 4026 | 6.68# (6.48-6.89) | 6252 | 1114 | 2.70# (2.54-2.86) | 4089 | 1006 | 1.82# (1.71-1.94) | 1305 | 225 | 1.58# (1.38-1.81) |
| Papillary transitional cell carcinoma | 8540 | 5761 | 3.69# (3.6-3.79) | 8540 | 1821 | 6.69# (6.39-7) | 6671 | 2166 | 4.82# (4.62-5.03) | 4435 | 814 | 2.59# (2.42-2.78) | 2921 | 778 | 1.86# (1.73-1.99) | 961 | 182 | 1.72# (1.48-1.99) |
| Squamous cell carcinoma | 765 | 615 | 7.66# (7.07-8.29) | 765 | 374 | 23.87# (21.51-26.41) | 385 | 147 | 7.92# (6.69-9.31) | 237 | 36 | 2.31# (1.62-3.2) | 173 | 51 | 2.12# (1.58-2.79) | 52 | 7 | 1.09 (0.44-2.24) |
| Small cell carcinoma | 421 | 317 | 6.44# (5.75-7.19) | 421 | 144 | 13.90# (11.72-16.37) | 276 | 119 | 8.74# (7.24-10.46) | 152 | 29 | 3.16# (2.11-4.53) | 95 | 22 | 1.64# (1.03-2.49) | 27 | 3 | 1.13 (0.23-3.3) |
| Transitional cell carcinoma, spindle cell | 263 | 194 | 7.43# (6.42-8.55) | 263 | 114 | 21.65# (17.86-26.01) | 147 | 55 | 7.32# (5.52-9.53) | 90 | 12 | 2.22# (1.15-3.89) | 65 | 11 | 1.72 (0.86-3.07) | 15 | 2 | 1.29 (0.16-4.65) |
| Surgery | ||||||||||||||||||
| Partial cystectomy | 1179 | 713 | 3.15# (2.92-3.39) | 1179 | 186 | 5.38# (4.64-6.21) | 991 | 279 | 4.52# (4-5.08) | 699 | 116 | 2.35# (1.94-2.81) | 477 | 107 | 1.66# (1.36-2) | 145 | 25 | 1.56# (1.01-2.3) |
| Radical cystectomy | 7360 | 4668 | 3.89# (3.78-4.01) | 7360 | 1335 | 8.81# (8.34-9.29) | 5992 | 1830 | 6.60# (6.3-6.91) | 4107 | 596 | 2.53# (2.33-2.74) | 3063 | 714 | 1.74# (1.61-1.87) | 1195 | 193 | 1.56# (1.35-1.8) |
| Other therapy | 14166 | 11294 | 5.20# (5.11-5.3) | 14166 | 5101 | 10.13# (9.85-10.41) | 8983 | 3881 | 5.75# (5.58-5.94) | 4998 | 1170 | 2.86# (2.7-3.03) | 3028 | 957 | 2.00# (1.87-2.13) | 897 | 185 | 1.77# (1.52-2.04) |
| Chemotherapy | ||||||||||||||||||
| Yes | 10905 | 7181 | 5.11# (4.99-5.23) | 10905 | 2124 | 8.11# (7.77-8.46) | 8740 | 3320 | 7.71# (7.45-7.98) | 5322 | 900 | 3.08# (2.88-3.28) | 3165 | 727 | 2.09# (1.94-2.25) | 783 | 110 | 1.54# (1.26-1.85) |
| No/Unknown | 15641 | 11648 | 4.43# (4.35-4.51) | 15641 | 5185 | 10.41# (10.13-10.7) | 10356 | 3628 | 5.08# (4.91-5.25) | 6613 | 1259 | 2.51# (2.38-2.66) | 4643 | 1243 | 1.73# (1.63-1.83) | 1728 | 333 | 1.68# (1.5-1.87) |
| Radiation | ||||||||||||||||||
| Yes | 4693 | 3858 | 5.02# (4.86-5.18) | 4693 | 1428 | 7.50# (7.12-7.9) | 3245 | 1587 | 6.15# (5.85-6.46) | 1628 | 448 | 3.02# (2.75-3.31) | 887 | 351 | 2.34# (2.1-2.6) | 182 | 44 | 1.95# (1.42-2.62) |
| No/Unknown | 21853 | 14971 | 4.58# (4.51-4.66) | 21853 | 5881 | 10.33# (10.06-10.59) | 15851 | 5361 | 6.04# (5.88-6.21) | 10307 | 1711 | 2.65# (2.53-2.78) | 6921 | 1619 | 1.77# (1.68-1.85) | 2329 | 399 | 1.61# (1.46-1.78) |
NMIBC: Non-muscular invasive bladder cancer; non-MMIBC: non-metastatic muscle invasive bladder cancer; SMR: Standard Mortality Ratio;
#
significant difference.