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. 2022 May 15;14(5):3494–3515.

Table 4.

Main cause of deaths for patients with non-metastatic muscle invasive bladder cancer

Causes of deaths Total <1 year 1-3 years 3-5 years 5-10 years >10 years






Observed Expected SMR (95% CI) Observed Expected SMR (95% CI) Observed Expected SMR (95% CI) Observed Expected SMR (95% CI) Observed Expected SMR (95% CI) Observed Expected SMR (95% CI)
All Causes of Death 18,829 4,035.71 4.67# (4.6-4.73) 7,309 759.89 9.62# (9.4-9.84) 6,948 1,145.04 6.07# (5.93-6.21) 2,159 793.72 2.72# (2.61-2.84) 1,970 1,066.89 1.85# (1.77-1.93) 443 270.17 1.64# (1.49-1.8)
All Malignant Cancers 13,860 878.05 15.78# (15.52-16.05) 5,754 168.26 34.20# (33.32-35.09) 5,629 256.85 21.92# (21.35-22.5) 1,383 174.2 7.94# (7.53-8.37) 942 225.2 4.18# (3.92-4.46) 152 53.53 2.84# (2.41-3.33)
    Urinary Bladder 11,797 35.78 329.74# (323.82-335.75) 5,232 6.5 805.31# (783.63-827.43) 4,852 10.08 481.36# (467.91-495.09) 1,065 7.08 150.41# (141.51-159.73) 590 9.65 61.12# (56.29-66.26) 58 2.47 23.51# (17.85-30.4)
    Lung and Bronchus 435 237.33 1.83# (1.66-2.01) 45 46.94 0.96 (0.7-1.28) 147 71.2 2.06# (1.74-2.43) 86 47.15 1.82# (1.46-2.25) 119 58.9 2.02# (1.67-2.42) 38 13.13 2.89# (2.05-3.97)
Prostate 192 87.03 2.21# (1.91-2.54) 64 16.55 3.87# (2.98-4.94) 82 24.95 3.29# (2.61-4.08) 18 17.1 1.05 (0.62-1.66) 23 22.62 1.02 (0.64-1.53) 5 5.8 0.86 (0.28-2.01)
    Kidney and Renal Pelvis 95 22.19 4.28# (3.46-5.23) 38 4.16 9.15# (6.47-12.55) 29 6.46 4.49# (3-6.44) 14 4.43 3.16# (1.73-5.31) 11 5.77 1.91 (0.95-3.41) 3 1.38 2.18 (0.45-6.37)
    Colon and Rectum 89 76.66 1.16 (0.93-1.43) 13 15.25 0.85 (0.45-1.46) 34 22.66 1.50# (1.04-2.1) 10 15.11 0.66 (0.32-1.22) 24 19.17 1.25 (0.8-1.86) 8 4.48 1.79 (0.77-3.52)
    Pancreas 82 56.67 1.45# (1.15-1.8) 13 10.43 1.25 (0.66-2.13) 34 16.34 2.08# (1.44-2.91) 19 11.32 1.68# (1.01-2.62) 15 14.95 1 (0.56-1.66) 1 3.63 0.28 (0.01-1.53)
    Colon excluding Rectum 75 63.04 1.19 (0.94-1.49) 11 12.64 0.87 (0.43-1.56) 30 18.66 1.61# (1.08-2.29) 8 12.4 0.65 (0.28-1.27) 19 15.68 1.21 (0.73-1.89) 7 3.65 1.92 (0.77-3.95)
    Liver and Intrahepatic Bile Duct 39 32.44 1.2 (0.85-1.64) 6 5.72 1.05 (0.38-2.28) 8 9.28 0.86 (0.37-1.7) 15 6.54 2.29# (1.28-3.78) 8 8.76 0.91 (0.39-1.8) 2 2.14 0.93 (0.11-3.37)
    Esophagus 38 25.89 1.47# (1.04-2.01) 4 4.84 0.83 (0.23-2.12) 8 7.63 1.05 (0.45-2.07) 7 5.19 1.35 (0.54-2.78) 15 6.68 2.25# (1.26-3.71) 4 1.56 2.57 (0.7-6.58)
    Stomach 34 17.03 2.00# (1.38-2.79) 7 3.39 2.06 (0.83-4.25) 9 5.06 1.78 (0.81-3.38) 8 3.36 2.38# (1.03-4.69) 7 4.24 1.65 (0.66-3.4) 3 0.98 3.06 (0.63-8.95)
    Leukemia 30 39.58 0.76 (0.51-1.08) 1 7.44 0.13# (0-0.75) 10 11.4 0.88 (0.42-1.61) 5 7.85 0.64 (0.21-1.49) 10 10.38 0.96 (0.46-1.77) 4 2.51 1.6 (0.44-4.09)
    Ureter 21 0.78 26.89# (16.64-41.1) 9 0.14 63.55# (29.06-120.63) 7 0.22 31.78# (12.78-65.47) 3 0.15 19.40# (4-56.71) 1 0.21 4.75 (0.12-26.45) 1 0.05 18.53 (0.47-103.26)
    Breast 20 22.44 0.89 (0.54-1.38) 7 4.61 1.52 (0.61-3.13) 5 6.58 0.76 (0.25-1.77) 0 4.38 0.00# (0-0.84) 7 5.58 1.25 (0.5-2.59) 1 1.31 0.77 (0.02-4.27)
    Lymphoma 20 36.51 0.55# (0.33-0.85) 1 6.97 0.14# (0-0.8) 2 10.58 0.19# (0.02-0.68) 9 7.22 1.25 (0.57-2.37) 7 9.45 0.74 (0.3-1.53) 1 2.28 0.44 (0.01-2.44)
    Non-Hodgkin Lymphoma 20 35.11 0.57# (0.35-0.88) 1 6.71 0.15# (0-0.83) 2 10.17 0.20# (0.02-0.71) 9 6.94 1.3 (0.59-2.46) 7 9.1 0.77 (0.31-1.59) 1 2.2 0.45 (0.01-2.53)
Non-malignant cancer
    Diseases of Heart 1,717 1,097.89 1.56# (1.49-1.64) 569 211.8 2.69# (2.47-2.92) 468 312.58 1.50# (1.36-1.64) 261 214.64 1.22# (1.07-1.37) 320 286.09 1.12 (1-1.25) 99 72.77 1.36# (1.11-1.66)
    Chronic Obstructive Pulmonary Disease and Allied Cond 561 256.78 2.18# (2.01-2.37) 162 48.03 3.37# (2.87-3.93) 137 73.21 1.87# (1.57-2.21) 108 50.75 2.13# (1.75-2.57) 122 67.94 1.80# (1.49-2.14) 32 16.86 1.90# (1.3-2.68)
    Cerebrovascular Diseases 290 226.65 1.28# (1.14-1.44) 83 43.8 1.89# (1.51-2.35) 89 63.89 1.39# (1.12-1.71) 38 44.11 0.86 (0.61-1.18) 62 59.33 1.04 (0.8-1.34) 18 15.52 1.16 (0.69-1.83)
    Nephritis, Nephrotic Syndrome and Nephrosis 170 85.62 1.99# (1.7-2.31) 46 16.3 2.82# (2.07-3.76) 41 24.39 1.68# (1.21-2.28) 26 16.82 1.55# (1.01-2.27) 46 22.47 2.05# (1.5-2.73) 11 5.64 1.95 (0.97-3.49)
    Alzheimers 167 171.54 0.97 (0.83-1.13) 39 29.63 1.32 (0.94-1.8) 35 45.18 0.77 (0.54-1.08) 27 33.26 0.81 (0.54-1.18) 54 49.03 1.1 (0.83-1.44) 12 14.44 0.83 (0.43-1.45)
    Septicemia 165 57.39 2.88# (2.45-3.35) 80 10.77 7.43# (5.89-9.24) 39 16.32 2.39# (1.7-3.27) 20 11.31 1.77# (1.08-2.73) 21 15.13 1.39 (0.86-2.12) 5 3.85 1.3 (0.42-3.03)
    Pneumonia and Influenza 163 101.66 1.60# (1.37-1.87) 50 20.02 2.50# (1.85-3.29) 41 28.89 1.42# (1.02-1.93) 25 19.78 1.26 (0.82-1.87) 35 26.32 1.33 (0.93-1.85) 12 6.65 1.8 (0.93-3.15)
    Diabetes Mellitus 153 113.58 1.35# (1.14-1.58) 44 21.52 2.05# (1.49-2.75) 43 32.75 1.31 (0.95-1.77) 32 22.47 1.42 (0.97-2.01) 26 29.54 0.88 (0.57-1.29) 8 7.3 1.1 (0.47-2.16)
    Accidents and Adverse Effects 127 112.61 1.13 (0.94-1.34) 30 20.29 1.48 (1-2.11) 36 31.64 1.14 (0.8-1.58) 28 22.26 1.26 (0.84-1.82) 22 30.48 0.72 (0.45-1.09) 11 7.94 1.39 (0.69-2.48)
    Hypertension without Heart Disease 89 47.1 1.89# (1.52-2.33) 27 8.48 3.19# (2.1-4.64) 21 12.91 1.63# (1.01-2.49) 11 9.24 1.19 (0.59-2.13) 24 12.98 1.85# (1.18-2.75) 6 3.48 1.72 (0.63-3.75)
    Symptoms, Signs and Ill-Defined Conditions 83 47.07 1.76# (1.4-2.19) 33 9.13 3.61# (2.49-5.08) 27 13.35 2.02# (1.33-2.94) 10 9.27 1.08 (0.52-1.98) 10 12.51 0.8 (0.38-1.47) 3 2.82 1.06 (0.22-3.11)
    Other Infectious and Parasitic Diseases including HIV 78 29.52 2.64# (2.09-3.3) 40 5.72 7.00# (5-9.53) 18 8.7 2.07# (1.23-3.27) 5 5.85 0.85 (0.28-1.99) 13 7.52 1.73 (0.92-2.95) 2 1.73 1.16 (0.14-4.19)
    Suicide and Self-Inflicted Injury 67 24.58 2.73# (2.11-3.46) 24 4.51 5.32# (3.41-7.92) 20 7.26 2.76# (1.68-4.26) 9 4.96 1.82 (0.83-3.45) 13 6.37 2.04# (1.09-3.49) 1 1.49 0.67 (0.02-3.73)

Abbreviations: SMR, standardized mortality ratio; CI, confidence interval;

#

significant difference.