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. 2022 Jun 7;28(21):2396–2402. doi: 10.3748/wjg.v28.i21.2396

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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

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Histologic and molecular findings. A: The lesion was composed of nests and cords of polygonal cells with abundant granular cytoplasm, and occasional mitotic figures in the more cellular areas, hematoxylin and eosin original magnification (O.M) × 60; B: Chromogranin A (CgA) positivity in neoplastic cells; inset: Synaptophysin positivity in neoplastic cells, CgA stain, O.M × 10; C: GATA-3 positivity in neoplastic cells, GATA-3 stain, O.M. × 10; D: S100-positive cells were scattered; inset: Succinate dehydrogenase subunit B (SDHB) expression was preserved, S100 stain, O.M. × 10; inset, SDHB stain, O.M. × 10; E: KDR mutation; F: JAK3 mutation.