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. 2022 May 22;4(3):fcac135. doi: 10.1093/braincomms/fcac135

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© The Author(s) 2022. Published by Oxford University Press on behalf of the Guarantors of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Association between plasma GFAP levels and Aβ-SUVR values stratified by APOE genotype. SUVR, standardized uptake value ratio; GFAP, glial fibrillary acidic protein. Co-variation of plasma GFAP and Aβ-PET retention extracted from the same location of the MRS volume. The participants were stratified in APOE ε4 carriers and non-carriers (Aβ-PET∼GFAP: P < 0.001 in APOE ε4 carriers, P < 0.001 in APOE ε4 non-carriers). The analysis was run in a subset of 288 participant with available plasma GFAP. The translucent area around the regression line represents the 95% confidential interval for the regression estimate.