Figure 1.

No strong association was observed between tumor proliferation and Apical Junction Pathway score. (A) With TCGA cohort, there was no difference in MKI67 expression and Grade between high and low Apical Junction Pathway score groups. With the GSE84437 cohort, while MKI67 expression and proliferation were higher in the low Apical Junction Pathway score group (P<0.001, respectively). (B) None of proliferation related gene sets, including G2M CHECKPOINT, MYC TARGETS V1/V2 and E2F TARGET were enriched in the high Apical Junction Pathway score group on GSEA (B). TCGA, the cancer genomic atlas; GSEA, gene set enrichment analysis.