Table 3.

Correlation analysis of OS-related radiomics signature with clinical parameters

Variables	Development cohort (n = 145)			Validation cohort (n = 51)
	Low Rad-score group	High Rad-score group	P	Low Rad-score group	High Rad-score group	P
Gender			0.491			0.693
Male	55	22		21	8
Female	52	16		17	5
Age, years			0.257			0.286
≤ 60	42	11		15	3
> 60	65	27		23	10
Tumor location			0.009			0.005
head	97	28		34	7
body and tail	10	10		4	6
Maximum diameter of tumor			0.965			0.811
≤ 4 cm	68	24		19	6
> 4 cm	39	14		19	7
Differentiated degree			< 0.001			0.014
High	15	0		7	0
Medium	75	17		25	6
Low	17	21		6	7
AJCC staging			< 0.001			0.085
I	23	0		7	0
II	73	23		27	9
III	11	15		4	4
T staging			0.643			0.869
T1	16	8		5	1
T2	52	16		14	5
T3	39	14		19	7
N staging			< 0.001			0.120
N0	42	7		15	2
N1	53	16		19	7
N2	12	15		42	4
Vascular invasion			0.007			0.121
No	61	12		24	5
Yes	46	26		14	8
Nerve invasion			0.325			0.017
No	55	16		26	4
Yes	52	22		12	9
BMI (Kg/m2)			0.743			0.940
< 24	54	18		20	7
≥ 24	53	20		18	6
CEA (ng/ml)			0.053			0.159
≤ 5	31	5		10	1
> 5	76	33		28	12
CA19-9 (U/ml)			0.010			0.577
≤ 37	54	10		18	5
> 37	53	28		20	8
Smoking history			0.715			0.363
No	82	28		24	10
Yes	25	10		14	3
Drinking history			0.655			0.650
No	80	27		26	8
Yes	27	11		12	5
Hypertension			0.595			0.756
No	71	27		28	9
Yes	36	11		10	4
Diabetes			0.777			0.756
No	85	31		28	9
Yes	22	7		10	4
Clinical symptoms			0.936			0.433
No	6	2		3	2
Yes	101	36		35	11