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. 2022 May 15;12(5):1934–1959.

Figure 4.

Figure 4

Identification of circRNA expression profiles in PDAC cells treated with Exo. (A) Microarray analysis of the effect of Exo treatment on circRNA expression in CFPAC-1 cells. (B) Sequence information of circ_6790. (C) circ_6790 expression in PANC-1 cells upon Exo treatment determined using RT-qPCR. (D) circ_6790 is present in exosomes. (E) The enrichment of circ_6790 in Exo and BM-MSC examined using RT-qPCR. (F) Detection of circ_6790 expression in PDAC cells by RT-qPCR. (G) The expression of circ_6790 and MEMO1 in PDAC cells upon RNase R treatment measured using RT-qPCR. (H) The expression profile of circ_6790 in BM-MSC upon si-circ treatment measured using RT-qPCR. (I) Detection of circ_6790 expression in Exo-Ctr and Exo-KD by RT-qPCR. *P < 0.05. Data are shown as mean ± SD of three technical replicates. Unpaired t-test (C, E, H, I) and one-way (F) or two-way ANOVA (G) were used for data comparison.