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. 2022 May 15;12(5):1934–1959.

Figure 6.

Figure 6

circ_6790 promotes CBX7 nuclear translocation. A. The localization of circ_6790 in PDAC cells examined using subcellular fractionation. B. The RBP of circ_6790 predicted using StarBase and RBP suite. C. Correlation of CBX7, HNRNPC, IGF2BP2 expression and survival of PDAC patients. D. The binding ability of CBX7, HNRNPC, and IGF2BP2 to circ_6790 assessed using RIP assay. E. Correlation of CBX7 expression with the level of immune infiltration of PDAC. F. Co-localization of circ_6790 and CBX7 detected by FISH combined with immunofluorescence. G. Western blot detection of CBX7 protein expression in PDAC cells co-cultured with Exo. H. Western blot detection of CBX7 protein expression in the cytoplasm and nucleus of PDAC cells co-cultured with Exo. *P < 0.05. Data are shown as mean ± SD of three technical replicates. Two-way ANOVA was used for data comparison.