Figure 8.

The circ_6790/CBX7/S100A11 axis regulates the growth and metastases of PDAC. (A) circ_6790, CBX7, and S100A11 expression in PDAC cells after different treatments examined using RT-qPCR. (B) The proliferation of cells evaluated by CCK8 assay. (C) The clonogenic ability of cells examined using colony formation assay. (D) The apoptosis rate of cells by flow cytometry. (E) The cell migration of cells examined using wound healing assay. (F) Cell invasiveness examined using Transwell assays. (G) Volume changes of xenograft tumors. (H) Weight of xenograft tumors. (I) The area of tumor infiltration in the liver and lungs of nude mice. *P < 0.05. Data are shown as mean ± SD of three technical replicates (n = 5). One-way (C-F, H) or two-way ANOVA (A, B, G, I) were used for data comparison.