Figure 10.

Schematic showing the three main methods used for radiolabeling of the cell surface for direct cell radiolabeling. (A) Radionuclides can be covalently attached to surface proteins or (B) radiolabeled antibodies can bind to receptors on the cell surface. Additionally, (C) compounds can be designed to intercalate into the lipid bilayers on the cells surface allowing radiolabeling. (D) Structures of the radioactive compounds used for covalent attachment to the cell surface. (E) Structures of radioactive compounds that can intercalate into the lipid bilayer on cells allowing radiolabeling. Panel A was made using Biorender.com.