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(A) Chemical structures of all ionophore ligands discussed in this Review along with the corresponding radionuclides used for cell labeling. (B) Chemical structures of key radiometal–ionophore complexes and chemical compounds used for radiometal–ionophore cell radiolabeling. Note that while [99mTc]Tc-HMPAO has been categorized as a radiometal–ionophore complex, the exact cellular trapping mechanism is not known.
