Table 4.

Candidate natural compounds and phytochemicals related to impaired FSHD molecular targets.

Target Molecule	Natural Compound/Phytochemical	References
TNF-α IL-1B	Curcumin	[131]
NFκB	Curcumin, delphinidin	[134, 135, 143]
Smi1 (PRC2)	Curcumin	[136]
P300	Curcumin, delphinidin, garcinol, anacardic acid, gallic acid and epigallocatechin-3-gallate (ECGC)	[137, 139-143]
STAT3	Cryptotanshinone, curcumin, ursolic acid, cucurbitacin E, alantolactone, silibinin and piperlongumine	[142-147]
DNMTs	Resveratrol, schizandrol A (1 or 3 ug/ul)	[145, 146]
miR-206 PAX7	TRF (25% alpha tocopherol and 75% tocotrienols)	[148]