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. 2022 Apr 27;71(7):1426–1439. doi: 10.1136/gutjnl-2021-326784

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Impact of inflammatory bowel disease (IBD) treatments on SARS-CoV-2 vaccine response. GMR spike antibody concentration calculated from multivariable linear regression models comparing the magnitude of spike (S) antibody responses in each medication class to healthy controls. GMR is thought to be equivalent to a fold-change in antibodies. Shaded red boxes represent IBD medications with attenuated vaccine response. Figure created based on data from refs.137 143–146 154 175 using BioRender.com. anti-TNF, anti-tumour necrosis factor; 5-ASA, 5-aminosalicylic acid; GMR, geometric mean ratio; JAK-inhibitor, Janus kinase inhibitor.