Table 1.
Overall demographics and preoperative clinical manifestations.
| Variables | Overall (n = 98) | Craniopharyngioma (n = 48) | RCC (n = 19) | Pituitary adenoma (n = 16) | Germinoma (n = 8) | Chordoma (n = 3) | LCH (n = 2) | Others (n = 2) | P-value |
|---|---|---|---|---|---|---|---|---|---|
| Median age (yrs, range) | 12 (4-18) | 12 (4-18) | 10 (6-17) | 14 (10-17) | 12 (9-15) | 7 (6-10) | 10 (10-11) | 11 (6-16) | .056 |
| Sex (%) | .415 | ||||||||
| Male | 52 (53) | 30 (62) | 9 (47) | 6 (38) | 2 (25) | 2 (67) | 1 (50) | 2 (100) | |
| Female | 46 (47) | 18 (38) | 10 (53) | 10 (62) | 6 (75) | 1 (33) | 1 (50) | – | |
| Median follow-up duration (months) | 59 | 58 | 41 | 68 | 74 | 100 | 50 | 93 | .633 |
| Hydrocephalus* (%) | 11 (11) | 10 (21) | – | – | 1 (9) | – | – | – | .041 |
| Visual status† (%) | .164 | ||||||||
| Normal | 45 (46) | 19 (40) | 8 (42) | 9 (56) | 5 (62) | 2 (67) | 1 (50) | 1 (50) | |
| Disturbed | 53 (54) | 29 (60) | 11 (58) | 7 (44) | 3 (38) | 1 (33) | 1 (50) | 1 (50) | |
| Anterior pituitary function‡ (%) | .023 | ||||||||
| Normal | 29 (30) | 7 (15) | 7 (36) | 10 (62) | 3 (38) | 2 (67) | – | – | |
| Partial deficiency | 28 (29) | 15 (31) | 6 (32) | – | 3 (38) | 1 (33) | 2 (100) | 1 (50) | |
| Panhypopituitarism | 41 (41) | 26 (54) | 6 (32) | 6 (38) | 2 (24) | – | – | 1 (50) | |
| Diabetes insipidus§ (%) | 32 (33) | 20 (42) | 5 (26) | – | 7 (88) | – | – | – | .153 |
*Includes headache, seizure, altered consciousness.
†Includes blurred vision, visual field defect.
‡Includes amenorrhea, galactorrhea, sudden weight gain, short stature, morphologic change.
§Includes polydipsia, polyuria.
RCC, Rathke's cleft cyst; LCH, Langerhans cell histiocytosis.