Table 3.
Postoperative neuroendocrine outcomes and complications.
| Variables (%) | Overall (n = 98) | Craniopharyngioma (n = 48) | RCC (n = 19) | Pituitary adenoma (n = 16) | Germinoma (n = 8) | Chordoma (n = 3) | LCH (n = 2) | Others (n = 2) | P-value |
|---|---|---|---|---|---|---|---|---|---|
| Visual outcome | .279 | ||||||||
| Improved* | 39/53 (74) | 21/29 (72) | 10/11 (91) | 4/7 (57) | 2/3 (67) | 1/1 (100) | 1/1 (100) | 0/1 (0) | |
| No change | 57 (58) | 25(52) | 9 (47) | 12 (75) | 6 (75) | 2 (67) | 1 (50) | 2 (100) | |
| Aggravated | 2 (2) | 2 (4) | – | – | – | – | – | ||
| Anterior pituitary function | .047 | ||||||||
| Improved† | 12/69 (17) | 4/41 (10) | 1/12 (8) | 4/6 (67) | 0/5 (0) | 1/1 (100) | 2/2 (100) | 0/2 (0) | |
| No change | 52 (53) | 23 (48) | 12 (63) | 11 (69) | 3 (38) | 2 (67) | – | 1 (50) | |
| Aggravated | 34 (35) | 21 (44) | 6 (32) | 1 (6) | 5 (62) | – | – | 1 (50) | |
| Diabetes insipidus | .018 | ||||||||
| Improved‡ | 4/32 (13) | 1/20 (5) | 1/5 (20) | – | 2/7 (29) | – | – | – | |
| New onset§ | 27/66 (41) | 24/28 (86) | 1/14 (7) | 1/16 (6) | 1/1 (100) | 0/3 (0) | 0/2 (0) | 0/2 (0) | |
| Complications | .007 | ||||||||
| CSF leak | 2 (2) | – | 2 (11) | – | – | – | – | – | |
| meningitis | 12 (12) | 11 (23) | – | – | 1 (13) | – | – | – | |
| Vasospasm | 1 (1) | 1 (2) | – | – | – | – | – | – | |
| Hemorrhage | 1 (1) | 1 (2) | – | – | – | – | – | – | |
| Infarction | 1 (1) | 1 (2) | – | – | – | – | – | – | |
| Recurrence | 18 (18) | 10 (21) | 2 (11) | 3 (19) | 1 (13) | 1 (33) | – | 1 (50) | .860 |
*Percentage based on patients with only preoperative visual disturbance.
†Percentage based on patients with only preoperative anterior pituitary insufficiency.
‡Percentage based on patients with only preoperative diabetes insipidus.
§Percentage based on patients without preoperative diabetes insipidus.
RCC, Rathke's cleft cyst; LCH, Langerhans cell histiocytosis.