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. 2022 May 6;9(6):841–852. doi: 10.1002/acn3.51564

Table 4.

Relationship between brain metabolites and memory performance.

Within normal limits (>16th %ile) Mildly impaired (16th–2nd %ile) Severely impaired (<2nd %ile) Total (%)
Ventricular lactate and verbal memory performance: p = 0.40
Within normal limits (≤ 4.8 i.u.) 34 11 2 47 (49.0)
High (4.8–5.7 i.u.) 14 5 1 20 (20.8)
Very high (≥ 5.7 i.u.) 17 7 5 29 (30.2)
Total (%) 65 (67.7) 23 (24.0) 8 (8.3) n = 96
Ventricular Lactate and Visual Memory Performance: p < 0.0001
Within normal limits (≤ 4.8 i.u.) 29 10 8 47 (49.0)
High (4.8–5.7 i.u.) 16 2 2 20 (20.8)
Very high (≥ 5.7 i.u.) 5 7 17 29 (30.2)
Total (%) 50 (52.1) 19 (19.8) 27 (28.1) n = 96
Occipital lactate and verbal memory performance: p = 0.45
Within normal limits (≤ 4.5 i.u.) 45 17 4 66 (68.7)
High (4.5–5.4 i.u.) 11 4 1 16 (16.7)
Very high (≥ 5.4 i.u.) 9 2 3 14 (14.6)
Total (%) 65 (67.7) 23 (24.0) 8 (8.3) n = 96
Occipital lactate and visual memory performance: p = 0.01
within normal limits (≤ 4.5 i.u.) 40 14 12 66 (68.7)
High (4.5–5.4 i.u.) 7 3 6 16 (16.7)
Very high (≥ 5.4 i.u.) 3 2 9 14 (14.6)
Total (%) 50 (52.1) 19 (19.8) 27 (28.1) n = 96
Occipital NAA and verbal memory performance: p = 0.44
Low (≤14.0 i.u.) 15 6 4 25 (26.0)
Within normal limits (14.0–17.6 i.u.) 27 10 1 38 (39.6)
High (≥ 17.6 i.u.) 23 7 3 33 (34.4)
Total (%) 65 (67.7) 23 (24.0) 8 (8.3) n = 96
Occipital NAA and visual memory performance: p = 0.002
Low (≤14.0 i.u.) 10 1 14 25 (26.0)
Within normal limits (14.0–17.6 i.u.) 19 13 6 38 (39.6)
High (≥ 17.6 i.u.) 21 5 7 33 (34.4)
Total (%) 50 (52.1) 19 (19.8) 27 (28.1) n = 96