Table 4. Univariate analysis of 90-day mortality in the Hokkaido University series.
| Characteristics | Hokkaido University | AMC/MSKCC 2015 (POMRS) | ||||
|---|---|---|---|---|---|---|
| No 90-day mortality (n=243) | 90-day mortality (n=11) | P | No 90-day mortality (n=247) | 90-day mortality (n=40) | ||
| Sex (male/female), n [%] | 171 [70]/75 [30] | 8 [83]/3 [27] | 0.821 | 151 [61]/96 [39] | 31[78]/9[22] | |
| Age (years) | 68 [43–86] | 69 [56–79] | 0.478 | 61.9 ±10.9 | 67.4±10.6 | |
| <50, n [%] | 7 [3] | 6 [55] | 0.903 | – | – | |
| 50–59, n [%] | 26 [11] | 1 [9] | – | – | ||
| 60–69, n [%] | 97 [40] | 4 [36] | – | – | ||
| 70–79, n [%] | 105 [43] | 6 [55] | – | – | ||
| ≥80, n [%] | 8 [3] | 0 | – | – | ||
| Body mass index | 21.9 [14.3–32.7] | 23.1 [19.6–27.3] | 0.198 | – | – | |
| FLRV (mL) | 613 [300–1,427] | 522 [295–730] | 0.071 | – | – | |
| FLRV (%) | 55.8 [28.5–95.4] | 48.7 [22–64.6] | 0.035 | – | – | |
| Large (>50%), n [%] | 142 [58] | 4 [36] | <0.001 | 105 [51] | 10 [29] | |
| Intermediate (30–50%), n [%] | 100 [41] | 6 [55] | 66 [32] | 10 [29] | ||
| Small (<30%), n [%] | 1 [0.4] | 1 [9] | 37 [18] | 15 [43] | ||
| Jaundice (yes/no), n [%] | 188 [77]/55 [23] | 11 [100]/0 | 0.128 | 202 [82]/47 [18] | – | |
| FLR drainage, n [%] (complete/incomplete) | 243 [100]/0 | 11[100]/0 | NA | 150 [72]/58 [28] | 23 [66]/12 [34] | |
| Preoperative cholangitis (yes/no), n [%] | 92 [38]/151 [62] | 4 [36]/7 [64] | 1.00 | 49 [20]/193 [80] | 10 [29]/25 [71] | |
| Type of liver resection, n [%] | ||||||
| Central | 1 [0.4] | 0 | 0.171 | 3 [1] | 3 [1] | |
| Left/Ext | 107 [44]/0 | 2 [18]/0 | 90 [36]/31 [13] | 12 [30]/5 [13] | ||
| L3 | 16 [2] | 1 [9] | – | – | ||
| Right/Ext | 109 [45]/0 | 6 [55]/0 | 40 [16]/83 [34] | 6 [15]/17 [43] | ||
| R3 | 10 [4] | 2 [18] | – | – | ||
| Operative time (min) | 665 [385–1,252] | 844 [607–1,250] | <0.001 | – | – | |
| Operative bleeding (mL) | 1,550 [390–1,590] | 3850 [2004–40,070] | <0.001 | – | – | |
| Portal vein reconstruction (yes/no), n [%] | 120 [49]/123 [51] | 8 [83]/3[27] | 0.126 | 51[18]/236[82] | 11[28]/29 [72] | |
| Hepatic artery reconstruction (yes/no), n [%] | 30 [12]/213 [88] | 2 [18]/9 [82] | 0.634 | – | – | |
| PHLF (yes/no), n [%] | 62 [25]/181 [75] | 9 [82]/2 [18] | <0.001 | – | – | |
Values are presented as n or median [range]. NA, not assessed; FLRV, future liver remnant volume; FLR, future liver remnant; central, central hepatectomy; left, left hepatectomy; L3, left trisectionectomy; right, right hepatectomy; R3, right trisectionectomy; PHLF, post-hepatectomy liver failure.